Glucagon Like Peptide-1 (Total) RIA
Description:
Glucagon Like Peptide-1 (Total) RIA
Background Information:
GLP-1 is secreted from gut endocrine cells in response to nutrient ingestion and plays multiple roles in metabolic homeostasis.
Key Applications:
Radioimmunoassay
Application Notes:
Two-day disequilibrium assay at 4°C. Sample volume = 300 µL plasma (extraction required)
Species Reactivity:
Mammals
Precision, %:
- Inter-assay: 10–23
- Intra-assay: 22–38
Therapeutic Areas:
- Diabetes
- Obesity
- Metabolic Disorders
Standard Curve Range:
10–1000 pM
Accuracy:
79–119%
Label:
125I-GLP-1
Kit Type:
Endocrine Kits
Gene Symbol:
- GCG
- GLP1
- glucagon
- GRPP
- GLP2
Detection Methods:
125I
Cross Reactivity:
GLP-1 is conserved in almost all mammals. This kit may be used to measure GLP-1 in these samples (e.g. rat, mouse, etc.)
Performance:
- ED80 = 14 ± 3 pM
- ED50 = 53 ± 6 pM
- ED20 = 224 ± 20 pM
Assay Type:
Radioimmunoassays (RIA)