Ultra Sensitive Human Insulin RIA
Description:
Ultra Sensitive Human Insulin RIA
Background Information:
Insulin, a 5.8 kDa hormone is secreted by the islet beta cells in the pancreas. This kit measures human insulin with high sensitivity but minimum cross-activity to proinsulin
Key Applications:
Radioimmunoassay
Application Notes:
Two-day disequilibrium incubation at room temperature. Sample volume 10 to 100 µL serum, plasma, or tissue culture media
Species Reactivity:
Human
Therapeutic Areas:
- Diabetes
- Obesity
- Metabolic Disorders
Label:
125I-Insulin
Standard Curve Range:
0.2–20 µU/mL
Specificity:
Human Insulin 100% Intact Human Proinsulin 6% Des 31, 32 HPI 6% Des 64, 65 HPI 78% Bovine Insulin 42% Bovine Proinsulin <2% Porcine Insulin 90% Porcine Proinsulin <5% Rat Insulin <1.0% IGF-1 Not Detectable Glucagon Not Detectable Somatostatin Not
Kit Type:
Endocrine Kits
Gene Symbol:
- INS
- proinsulin
- insulin
Detection Methods:
125I
Performance:
- ED80 = 0.9 ± 0.1 µU/ml
- ED50 = 3.1 ± 0.3 µU/ml
- ED20 = 12.1 ± 2.2 µU/ml
Assay Type:
Radioimmunoassays (RIA)