Ordering Information
- : HLPPMAG-57K
- : 96-well plate
MILLIPLEX MAP Human Liver Protein Magnetic Bead Panel - Metabolism Multiplex Assay
| Number of Analytes Available | Research Areas | Detection Methods |
|---|---|---|
| 9 | Cancer, Metabolic Disorders | Fluorescent, Luminex xMAP |
Description:
MILLIPLEX MAP Human Liver Protein Magnetic Bead Panel
Trade Name:
MILLIPLEX
Qty/Pk:
96-well plate
Product Overview:
Millipore’s MILLIPLEX MAP Human Liver Protein panel kit is to be used for the simultaneous quantification of AFP, ANGPTL3, ANGPTL4, ANGPTL6/AGF, HGF, FABP1/L-FABP, FGF-19, FGF-21, and FGF-23. This kit may be used for the analysis of all or any combination of the above analytes in tissue/cell lysate and culture supernatant samples and serum or plasma samples (note: when assaying ANGPTL6/AGF it is recommended that serum samples be used).
Background Information:
Liver-secreted proteins play important roles in metabolic regulation. For example, liver-secreted proteins have been shown to regulate circulating lipoprotein levels, energy expenditure, glucose metabolism, and fatty acid uptake. In addition, some liver-secreted proteins may also serve as biomarkers for liver diseases and gastric cancer. Accurate measurement of liver proteins is critical to obtain understanding of their biological functions.
Applications:
This MILLIPLEX® MAP Human Liver Protein Magnetic Bead Panel is a Metabolism multiplex assay. The analytes available for this multiplex kit are: AFP, ANGPTL3, ANGPTL4, ANGPTL6/AGF, FABP1, FGF-19, FGF-21, FGF-23, HGF.
Key Applications:
Multiplexing
Species Reactivity:
Human
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Configuration:
Design your multiplex kit by choosing from 9 analytes.
Sensitivity:
- AFP: 0.095 ng/mL
- ANGPTL3: 0.562 ng/mL
- ANGPTL4: 1.316 ng/mL
- ANGPTL6: 0.433 ng/mL
- HGF: 0.011 ng/mL
- FABP1: 0.113 ng/mL
- FGF-19: 0.043 ng/mL
- FGF-21: 0.003 ng/mL
- FGF-23: 0.283 ng/mL
Panel Type:
MAGNETIC Metabolism
Precision, %:
- Inter-assay: 7.5 - 18.4
- Intra-assay: 1.5 - 3.3
Accuracy:
- AFP 94.2%
- ANGPTL3 93.7%
- ANGPTL4 96.8%
- ANGPTL6 99.1%
- FGF-19 98.0%
- FGF-21 98.8%
- FGF-23 96.6%
- HGF 100.2%
Detection Methods:
- Fluorescent
- Luminex xMAP
Replaces:
This product replaces Human Liver Protein Panel, HLPP-57K in December of 2011 or while supplies last.
Cross Reactivity:
Cross-reactivities for the AFP, ANGPTL3, ANGPTL6, HGF, FABP1, FGF-19, FGF-21, and FGF-23 assays were not detectable or negligible. ANGPTL6 standard had cross reactivity with the ANGPTL4 assay of less than 2%.
Product Name:
MILLIPLEX MAP Human Liver Protein Magnetic Bead Panel
Standard Curve Range:
- 0.14 - 100 ng/mL: AFP & FGF-19
- 0.69 - 500 ng/mL: ANGPTL3
- 5.49 - 4000 ng/mL: ANGPTL4
- 1.37 - 1000 ng/mL: ANGPTL6 & FGF-23
- 0.07 - 50 ng/mL: HGF
- 0.27 - 200 ng/mL: FABP1
- 0.01 - 10 ng/mL: FGF-21
Analytes Available:
AFP, ANGPTL3, ANGPTL4, ANGPTL6/AGF, FABP1, FGF-19, FGF-21, FGF-23, HGF
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