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Ordering Information
- : MAB329
- : 100 µL
Product Images
Mouse anti-Synaptophysin (Catalog Number MAB329). Localization of synaptophysin (red) and Myelin Basic Protein (green) in human hippocampus (paraffin-...
Anti-Synaptophysin, clone SP15
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| H, Ht, Po, R | ELISA, WB, IH(P) | Mouse | Ascites | Monoclonal Antibody |
Description:
Anti-Synaptophysin, clone SP15
Trade Name:
Chemicon (Millipore)
Specificity:
Synaptophysin. Reacts with synaptophysin expressed in CHO cells.
Immunogen:
Crude synaptic immunoprecipitate (Human)
Clone:
SP15
Isotype:
IgM
Species Reactivity:
- Human
- Hamster
- Pig
- Rat
Application Notes:
Immunohistochemistry at 1:200-1:5,000.
Formalin fixed (fixed <4 weeks), paraffin embedded
Frozen
4% Paraformaldehyde
Western blotting at 1:2,500-1:10,000.
ELISA at 1:500
Optimal working dilutions must be determined by the end user.
Formalin fixed (fixed <4 weeks), paraffin embedded
Frozen
4% Paraformaldehyde
Western blotting at 1:2,500-1:10,000.
ELISA at 1:500
Optimal working dilutions must be determined by the end user.
Presentation:
Liquid
Storage Conditions:
Maintain frozen at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
UniProt Number:
Entrez Gene Number:
Gene Symbol:
- SYP
- synaptophysin
- Synaptophysin
Alternate Names:
Major Synaptic Vesicle Protein p38
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Entrez Gene Summary:
Synaptophysin (p38) is an integral membrane protein of small synaptic vesicles in brain and endocrine cells.[supplied by OMIM]
Key Applications:
- ELISA
- Western Blotting
- Immunohistochemistry (Paraffin)
UniProt Summary:
FUNCTION: SwissProt: P08247 # Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane.
SIZE: 313 amino acids; 33845 Da
SUBUNIT: Homohexamer or homotetramer.
SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype.
DOMAIN: SwissProt: P08247 The calcium-binding activity is thought to be localized in the cytoplasmic tail of the protein.
PTM: Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation (By similarity).
SIMILARITY: Belongs to the synaptophysin/synaptobrevin family. & Contains 1 MARVEL domain.
SIZE: 313 amino acids; 33845 Da
SUBUNIT: Homohexamer or homotetramer.
SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype.
DOMAIN: SwissProt: P08247 The calcium-binding activity is thought to be localized in the cytoplasmic tail of the protein.
PTM: Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation (By similarity).
SIMILARITY: Belongs to the synaptophysin/synaptobrevin family. & Contains 1 MARVEL domain.
Qty/Pk:
100 µL
Brand Family:
Chemicon
Format:
Ascites
Host:
Mouse
Product Name:
Anti-Synaptophysin, clone SP15
Antibody Type:
Monoclonal Antibody