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注文に関する情報
- : MAB6210
- : 1 mg
- : 5.4 mg/mL
Anti-Luteinizing Hormone
| 交差性 | 主要アプリケーション | 免疫動物 | フォーマット | 抗体タイプ |
|---|---|---|---|---|
| H | ELISA | Mouse | Purified | Monoclonal Antibody |
Description:
Anti-Luteinizing Hormone
Trade Name:
Chemicon (Millipore)
Specificity:
Human luteinizing hormone. Less than 0.01% cross reactivity to hCG and greater than 0.1% cross reactivity to FSH.
AFFINITY CONSTANT:
3.2 x 1010
AFFINITY CONSTANT:
3.2 x 1010
Immunogen:
Human pituitary gland
Clone:
090-10226
Isotype:
IgG1
Species Reactivity:
Human
Application Notes:
EIA: sensitivity <1 mIU/mL
Optimal working dilutions must be determined by the end user.
Optimal working dilutions must be determined by the end user.
Control:
Human pituitary gland
Purification Method:
Ammonium sulfate precipitation
Presentation:
Purified immunoglobulin. Liquid in 10 mM sodium phosphate, 150 mM NaCl, pH 7.4 with 0.1% sodium azide
Storage Conditions:
Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
UniProt Number:
Entrez Gene Number:
Gene Symbol:
- LHB
- hLHB
- LSH-B
- LH-B
- LSH-beta
- CGB4
Alternate Names:
LH
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Entrez Gene Summary:
This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism.
Key Applications:
ELISA
UniProt Summary:
FUNCTION: SwissProt: P01229 # Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.
SIZE: 141 amino acids; 15345 Da
SUBUNIT: Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin.
SUBCELLULAR LOCATION: Secreted.
TISSUE SPECIFICITY: Pituitary gland.
DISEASE:SwissProt: P01229 # Defects in LHB are a cause of hypogonadism [MIM:152780]. Hypogonadism is characterized by infertility and pseudohermaphroditism.
SIMILARITY: SwissProt: P01229 ## Belongs to the glycoprotein hormones subunit beta family.
SIZE: 141 amino acids; 15345 Da
SUBUNIT: Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin.
SUBCELLULAR LOCATION: Secreted.
TISSUE SPECIFICITY: Pituitary gland.
DISEASE:SwissProt: P01229 # Defects in LHB are a cause of hypogonadism [MIM:152780]. Hypogonadism is characterized by infertility and pseudohermaphroditism.
SIMILARITY: SwissProt: P01229 ## Belongs to the glycoprotein hormones subunit beta family.
Qty/Pk:
1 mg
Brand Family:
Chemicon
Format:
Purified
Host:
Mouse
Product Name:
Anti-Luteinizing Hormone
Concentration:
5.4 mg/mL
Antibody Type:
Monoclonal Antibody