0 Items| Favorites
> Last Item Added:
0 Items

Ordering Information

  • : MSCR-42K
  • : 96-well plate

MILLIPLEX MAP Mouse Soluble Cytokine Receptor Panel

Number of Analytes Available Research Areas Detection Methods
13 Obesity, Metabolic Disorders, Inflammation Luminex xMAP
Description:
MILLIPLEX MAP Mouse Soluble Cytokine Receptor Panel
Trade Name:
MILLIPLEX
Qty/Pk:
96-well plate
Background Information:
Cytokines play a fundamental role in the pathogenesis of many diseases and are key targets for drug development. The discovery that soluble cytokine receptors are involved in regulating excessive inflammatory responses and modulating immune events has stimulated significant research interest in their potential role as immunotherapeutic agents. Many of these soluble cytokine receptors have the ability to inhibit the binding and biological activity of their cytokine ligands, making them very specific cytokine antagonists. The Mouse Soluble Cytokine Receptor Multiplex Panel quantitatively measures the following soluble cytokine receptor biomarkers in mouse serum, plasma, cell/tissue culture supernatant, tissue/cell lysate, or other body fluid samples
Key Applications:
Multiplexing
Application Notes:
25 µL sample volume 1:5 serum or plasma in assay buffer; 25 µL cell/tissue culture supernatant
Species Reactivity:
Mouse
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Configuration:
Design your multiplex kit by choosing from 13 analytes.
Linearity of Dilution:
Contact Technical Service for this information
Sensitivity:
  • sCD30 - 9 pg/ml
  • sgp130 - 84 pg/ml
  • sIL-1RI - 3 pg/ml
  • sIL-1RII - 11 pg/ml
  • sIL-2Rα - 6 pg/ml
  • sIL-4R - 3 pg/ml
  • sIL-6R - 24 pg/ml
  • sRAGE - 24 pg/ml
  • sTNFRI - 22 pg/ml
  • sTNFRII - 5 pg/ml
  • sVEGFR1 - 76 pg/ml
  • sVEGFR2 - 33 pg/ml
  • sVEGFR3 - 42 pg/ml
Panel Type:
Cytokines/Chemokines
Precision, %:
  • Intra-assay: 5 - 9
  • Inter-assay: 6 - 10
Accuracy:
  • sCD30 - 94%
  • sgp130 - 82%
  • sIL-1Rl - 93%
  • sIL-1Rll - 100%
  • sIL-2Rα - 95%
  • sIL-4R - 100%
  • sIL-6R - 105%
  • sRAGE - 78%
  • sTNFRI - 103%
  • sTNFRII - 96%
  • sVEGFR1- 176%
  • sVEGFR2 - 103%
  • sVEGFR3 - 101%
Detection Methods:
Luminex xMAP
Cross Reactivity:
Non-detectable or negligible cross-reactivity within the panel
Product Name:
MILLIPLEX MAP Mouse Soluble Cytokine Receptor Panel
Standard Curve Range:
  • 4.9 - 20,000 pg/mL - sTNFRI
  • 12.2 - 50,000 pg/ml - sIL-1RI, sIL-1RII, sIL-2Rα, sIL-4R, sTNFRII, sCD30, sgp130, sIL-6R, sRAGE, sVEGFR1
  • 24.4 - 100,000 pg/ml - sVEGFR2, sVEGFR3
Analytes Available:
sCD30 (sTNFRSF8), sIL-1RI (sCD121a), sIL-1RII (sCD121b), sIL-2Rα (sCD25), sIL-4R (sCD124), sIL-6R (sCD126), sRAGE, sTNFRI (sTNFRSF1A), sTNFRII (sTNFRSF1B), sVEGFR1 (sFlt-1), sVEGFR2 (sFlk-1), sVEGFR3 (sFlt-4), sgp130

Product Resources

Related Services

Millipore Tagging Services

Using your own antibodies, Millipore’s Tagging Services Team will develop your custom capture and detection antibodies through our bead conjugation and biotinylation…Learn More »

BioMarker Services

Millipore’s BioMarker Services team has over 25 years of experience performing routine immunoassays including multiplex assays, RIAs, ELISAs & IRMAs…Learn More »

Product Support