Human PYY (Total) RIA
Description:
Human PYY (Total) RIA
Background Information:
Peptide YY (PYY), a 36-amino acid amidated peptide, is a member of PP family including pancreatic polypeptide (PP) and neuropeptide Y (NPY).
Key Applications:
Radioimmunoassay
Application Notes:
Two-day disequilibrium assay, incubation at 4°C Sample volume: 100 µL serum, plasma, or tissue culture sample
Species Reactivity:
Human
Precision, %:
- Inter-assay: 5.5–8.5
- Intra-assay: 2.9–9.4
Sensitivity:
10 pg/mL
Therapeutic Areas:
- Diabetes
- Obesity
- Metabolic Disorders
Accuracy:
83–111%
Standard Curve Range:
10–1280 pg/mL
Label:
125I-PYY
Specificity:
Human Pyy 1-36 100% Human PYY 3-36 100% [Pro34] PYY 100%[Leu31, Pro34] PYY 100% Rat/Porcine PYY 1-36 <0.1% Rat/Porcine PYY 3-36 <0.1% Human PP < 0.1% Human NPY <0.1% Human Leptin Not detectable Human Ghrelin Not detectable Human Insulin No
Kit Type:
Endocrine Kits
Gene Symbol:
- PYY
- PYY-I
- PYY1
Detection Methods:
125I
Kit or Assay Type:
- Endocrine Kits
- Radioimmunoassays (RIA)
Performance:
- ED80 = 37.2 ± 8 pg/mL
- ED50 = 110.9 ± 20 pg/mL
- ED20 = 333.8 ± 73 pg/mL
Assay Type:
Radioimmunoassays (RIA)