Bestellinformationen
Anti-FAK, BC3
| Speziesreaktivität | Hauptanwendungen | Wirt | Format | Antikörperart |
|---|---|---|---|---|
| Av, H, M, R | IP, IC | Rabbit | Purified | Polyclonal Antibody |
UniProt-Nummer:
UniProt Summary
FUNCTION: SwissProt: Q05397 # Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in incr
...
weitere anzeigen »
GenBank-Nummer:
Entrez Gene Summary
This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain
...
weitere anzeigen »
Description:
Anti-FAK, BC3
Specificity:
FAK
Key Applications:
- Immunoprecipitation
- Immunocytochemistry
Species Reactivity:
- Avian
- Human
- Mouse
- Rat
Isotype:
IgG
Immunogen:
A TrpE-Fak fusion protein containing amino acids 651-1028 of chicken FAK
Molecular Weight:
125kDa
Presentation:
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, with 0.05% sodium azide
Storage Conditions:
2 years at -20°C
Gene Symbol:
- PTK2
- pp125FAK
- FADK
- FAK1
- FAK
Quality Assurance:
routinely evaluated by immunoprecipitating FAK from 3T3 RIPA cell lysate, and subsequent immunoblot analysis using FAK antibody (Catalog #06-543).
Antibody Category:
Signaling
Antibody Sub-Category:
Cytoskeletal Signaling
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Trade Name:
Upstate (Millipore)
Format:
Purified
Host:
Rabbit
Antibody Type:
Polyclonal Antibody
Purification Method:
protein G chromatography