Informazioni per l’ordine
Anti-FAK, clone 4.47, agarose conjugate
| Specie riconosciute | Applicazioni fondamentali | Ospite | Forma | Tipo di anticorpo |
|---|---|---|---|---|
| H | IAP, IP | Mouse | Gel Immobilized | Monoclonal Antibody |
Numero UniProt:
UniProt Summary
FUNCTION: SwissProt: Q05397 # Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in incr
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Numero GenBank:
Entrez Gene Summary
This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain
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Description:
Anti-FAK, clone 4.47, agarose conjugate
Key Applications:
- Immunoaffinity Purification
- Immunoprecipitation
Application Notes:
Suitable for immunoprecipitation and affinity purification.
Species Reactivity:
Human
Presentation:
PBS containing 0.05% sodium azide
Storage Conditions:
2 years at 4°C
Gene Symbol:
- PTK2
- pp125FAK
- FAK
- FADK
- FAK1
Quality Assurance:
routinely evaluated by immunoprecipitating FAK from a mouse 3T3/A31 RIPA cell lysate, as confirmed by subsequent immunoblot analysis using anti-FAK (05-537)
Antibody Category:
Signaling
Antibody Sub-Category:
Cytoskeletal Signaling
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Trade Name:
Upstate (Millipore)
Format:
Gel Immobilized
Host:
Mouse
Product Overview:
Anti-FAK monoclonal antibody (05-537), covalently coupled to Protein G agarose by dimethyl-pimelimidate
Antibody Type:
Monoclonal Antibody