Milli-Q® Ultrapure Water Purification Systems

The standard for ultrapure water in the laboratory

New Features and Optional Accessories Add Control and Convenience

   • Backlit display for easy access to system information
   • Remote display for quality monitoring and operation up to 3 m (10') distance
   • Ergonomically designed point-of-use dispense trigger for easier water delivery and fixed-volume water dispense
   • The Milli-Q remote point-of-use dispenser for convenient delivery of ultrapure water up to 2.5 m (8') away from your Milli-Q system; can be wall-mounted, dispenser arm rotates 180° for total flexibility
   • Foot pedal for hands-free water delivery from a Milli-Q system or remote POU dispenser
   • Millipak Express 20 final filter for minimum ionic and organic contaminant release when used for sub-ppb analysis of volatile organics or endocrine disrupters
   • Pyrogard™ D UF filter reduces pyrogen levels in ultrapure water below 0.001 EU/mL and removes nucleases when connected to the outlet of a Milli-Q system

A Range of New Milli-Q Systems

Millipore has developed a range of Milli-Q ultrapure water systems designed to match specific water quality requirements. Each of the five new Milli-Q systems is designed to specifically target contaminants detrimental to particular applications such as HPLC, molecular biology and ICP-MS. The systems incorporate a high precision resistivity monitor that records conductivity or resistivity (compensated or not to 25 °C), and also feature a built-in TOC monitor with a 1 – 999 ppb detection range for accurate analysis of organics. Milli-Q resistivity and TOC meters are designed to take into account the suitability test requirements of USP 28-NF21. Validation and qualification services are available, and access to historical data via a computer interface is possible. All systems can be bench-operated, wall-mounted or bench-integrated for maximizing space requirements.

The Milli-Q Concept

Standard Purification Steps

All systems in the Milli-Q range employ a 3-step purification process:

Step 1:

Plug-in Q-Gard purification packs are tailored to the feedwater source to optimize the performance of downstream purification media to ensure consistent results.

Step 2:

Quantum application-specific cartridges remove ionic and organic contaminants down to trace levels.

Step 3:

Final purification of ultrapure water is carried out at the point-of-use by a pharmaceutical-grade, absolute 0.22 µm Millipak membrane filter that is recommended for most analytical applications.

Additional Purification Steps

UV Photo-oxidation:

The ultraviolet photo-oxidation process (UV at 254 and 185 nm) used in Milli -Q Gradient , Synthesis and Element Systems can effectively carry out the destruction of organic molecules, to reduce TOC levels to < 5 ppb, improving consistency and sensitivity in applications such as HPLC, IC, solid-phase extraction and UV spectroscopy.

Ultrafiltration:

Milli-Q Biocel and Synthesis Systems include a Pyrogard 5000 ultrafiltration cartridge for the production of pyrogen- and nuclease-free ultrapure water (<0.001  EU/mL), particularly important for life science or molecular biology applications.

Applications

   • Milli-Q Academic System – General laboratory applications
   • Milli-Q Gradient System – Analytical chemistry
   • Milli-Q Biocel System – Life science applications
   • Milli-Q Synthesis System – Molecular biology applications
   • Milli-Q Element System – Ultratrace analysis

Features (return to top)

Point-of-Use Dispenser Specifications (return to top)

Materials

Non-wetted Surfaces

Arm: Polyamide with fiberglass
Base: Aluminum
Load: Stainless steel

Wetted Surfaces

Tubing: Polyethylene

Valve: Acrylonitrile butadiene styrene copolymer

Dimensions

Tubing:

2.5 m (8')

POU Dispenser, L x W x D:

13 cm x 6.98 cm x 3.81 cm
(5.1" x 2.7" x 1.5")

Weight

1.65 kg (3.63 lb) dry
(without the load)
3 kg (6.61 lb)
with stainless steel load

Note: Point-of-Use dispenser flow rate may be slightly less than system flow rate.

Compliance With Regulatory Standards

Systems are UL and cUL listed under file E216983 in the “Laboratory Use Electrical Equipment Category”, and meet the requirements of UL 61010 standards. Systems conform to European Union CE directives 89/336/CEE (electromagnetic compatibility) and 72/23/CEE (electrical equipment within certain voltage limits). All systems are manufactured in ISO 9001 and ISO 14001 certified environments.