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Centricon Plus-70 Centrifugal Filter Units

Convenient alternative to dialysis, lyophilization, or precipitation

Applications

       • Concentrating and desalting
    chromatography column eluates
       • Concentrating monoclonal antibodies
       • Concentrating proteins or viruses from culture supernatants
       • Clarifying tissue homogenates and cell lysates
       • Buffer exchange or diafiltration

Typical Flow Rates (return to top)

CC70PL30-71[40956-ALL].jpg

Ultracel PL-30 Membrane at 3,500 x g

Typical Retentate (Concentrate) Recovery
Membrane NMWLProtein SoluteProtein Retentate
10,000Cytochrome c, 12.4 kDa
(0.25 mg/mL)		94
30,000Bovine Serum Albumin,
67 kDa (1 mg/mL)		96
100,000IgG, 156 kDa
(1 mg/mL)		91

Specifications (return to top)

Volumes
Processing Volume, mL70
Final Concentration Volume, µL350
Hold-up Volume, µL75
Centrifugal ForceSwinging-bucket rotor (250 mL) w/maximum 3,500 x g
Materials
MembraneSee ordering information
DevicePolypropylene
Dimensions
Active Membrane Area, cm219
Diameter, mm60
Length, mm121
RecoveryTypically >90%
SanitizationRinse with 70% ethanol solution
Chemical CompatibilityUse with biological fluids only


Ordering Information  (return to top)

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