EGFR Antibodies, Kits & Proteins

EGFR (Epidermal growth factor receptor, ErbB-1) is a receptor tyrosine kinase (RTK), and is one of the EGFR/ErbB family of receptor tyrosine kinases. EGFR plays a role in the regulation of essential normal cellular processes and in the pathophysiology of hyperproliferative diseases such as cancer. EGFR is found in most solid tumors and it is known to be essential for mediation of both proliferative and survival signals to cells. Activation of the EGFR signaling pathway has been linked with increased cell proliferation, angiogenesis, metastasis and decreased apoptosis.