Millidisk Cartridge Filters

Description

Millidisk cartridge filters are stacked disc filters designed for the removal of particles and microorganisms from liquids and gases. The stacked disc design allows minimal hold-up volume and particle shedding, making Millidisk filters ideally suited for high-value added applications. All Millidisk filters are made with Durapore PVDF membranes, providing high flow rates and throughputs, low extractables, broad chemical compatibility and the lowest protein binding of any membrane available.

Millidisk filters are available in 0.1 µm, 0.22 µm (hydrophilic and hydrophobic), 0.45 µm and 5.0 µm pore sizes. Four available cartridge sizes allow optimum flexibility for easy scale up and system sizing. Millidisk filters are designed to be used with either Millidisk or Millidisk/Milligard housings.

For traceability and easy identification, each Millidisk filter is labelled with its catalogue number, lot number and serial number. Each unit is 100% integrity tested during manufacturing.

Typical Applications

Sterile filtration of parenterals, diagnostics and buffers
Sterile filtration of media and biologicals
Particle removal (clarification) of high value-added pharmaceuticals
Sterile filtration of non-aqueous liquids and gases with the hydrophobic units

Specifications

Materials of Construction
Filter	Hydrophilic PVDF
or	Hydrophobic PVDF
Support Discs and Adapter	Polysulfone
O-ring	Silicone
Connection
	Code M (2-118) O-rings
Filtration Area, cm²
Millidisk 10	500
Millidisk 20	1000
Millidisk 30	1500
Millidisk 40	2000
Maximum Differential Pressure, bar (psid)
	Forward: 4.1 (60) @ 25 °C; 1.7 (25) @ 80 °C; 0.35 (5) @ 123 °C. Reverse: 0.7 (10) @ 25 °C
Bacterial Retention (for Millidisk 0.1 µm and 0.22 µm only)
	Samples were quantitatively retentive of a minimum Brevundimonas diminuta challenge concentration of 1 x 10⁷ CFU/cm² using ASTM® F838 methodology.
Bacterial Endotoxins
	Aqueous extraction contains ≤0.5 EU/mL as determined by the Limulus Amebocyte Lysate (LAL) Test
Gravimetric Extractables
Millidisk 10	≤2.5 mg/unit
Millidisk 20	≤5.0 mg/unit
Millidisk 30	≤7.5 mg/unit
Millidisk 40	≤10.0 mg/unit
Oxidizable Substances
	Will meet the USP Oxidizable Substances Test requirements after a water flush of ≥200 mL
Toxicity
	Component materials meet the requirements of the USP Class VI Biological Test for Plastics. Millidisk units also meet the requirements of the USP General (Mouse) Safety Test.
Sterilization
	5 SIP cycles of 60 min @ 135 °C; 5 autoclave cycles of 60 min @ 126 °C
Integrity Test, Bubble Point
0.1 µm units	≥4830 mbar (70 psig) air with water
0.22 µm units	≥3450 mbar (50 psig) air with water
0.45 µm units	≥1790 mbar (26 psig) air with water
5 µm units	≥138 mbar (2 psig) air with water
0.22 µm hydrophobic units	≥1170 mbar (17.0 psig) nitrogen with 100% IPA

Typical Clean Water Flow Rate vs Pressure Drop

Millidisk 0.22 µm Hydrophobic Filters, Air Flow Rate at Ambient Temperature

Millidisk 0.1 µm Water Flow Rate

Millidisk 0.22 µm Water Flow Rate

Millidisk 0.22 µm Hydrophobic Water Flow Rate

Millidisk 0.45 µm Water Flow Rate

Millidisk 5.0 µm Water Flow Rate

Compare	Catalogue No.	Product Name	Qty/Pk
	MCVL10S03	Millidisk 10 Cartridge Filter	3
	MCVL20S03	Millidisk 20 Cartridge Filter	3
	MCVL30S03	Millidisk 30 Cartridge Filter	3
	MCVL40S03	Millidisk 40 Cartridge Filter	3

Compare	Catalogue No.	Product Name	Qty/Pk
	MCGL10S03	Millidisk 10 Cartridge Filter	3
	MCGL20S03	Millidisk 20 Cartridge Filter	3
	MCGL30S03	Millidisk 30 Cartridge Filter	3
	MCGL40S03	Millidisk 40 Cartridge Filter	3

Compare	Catalogue No.	Product Name	Qty/Pk
	MCHL10S03	Millidisk 10 Cartridge Filter	3
	MCHL20S03	Millidisk 20 Cartridge Filter	3
	MCHL30S03	Millidisk 30 Cartridge Filter	3
	MCHL40S03	Millidisk 40 Cartridge Filter	3

Compare	Catalogue No.	Product Name	Qty/Pk
	MCSL10S02	Millidisk 10 Cartridge Filter	2
	MCSL20S02	Millidisk 20 Cartridge Filter	2
	MCSL30S01	Millidisk 30 Cartridge Filter	1
	MCSL40S01	Millidisk 40 Cartridge Filter	1

Compare	Catalogue No.	Product Name	Qty/Pk
	MCGB10S02	Millidisk 10 Cartridge Filter	2
	MCGB20S02	Millidisk 20 Cartridge Filter	2
	MCGB30S01	Millidisk 30 Cartridge Filter	1
	MCGB40S01	Millidisk 40 Cartridge Filter	1

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