Viresolve Standard Modules

Description

Viresolve standard modules are self-contained, single-use disposable modules designed to remove viruses from protein solutions. Viresolve modules are fabricated from a single material of construction, polyvinylidene fluoride (PVDF). The modules are thermally bonded and no solvents are used in fabricating the units.

Viresolve modules achieve efficient virus removal while maximizing protein recoveries and minimizing hold-up volumes. The modules are used in a tangential flow filtration mode with two peristaltic pumps for superior transmembrane pressure control.

Each module is supplied with a medical-grade silicone tubing set and gaskets for easy connection to a variety of peristaltic pumps. The modules can be supplied in a number of configurations to meet a variety of process needs. For example, modules are available with accessories suitable for pressure monitoring or diafiltration processes.

Viresolve modules are available with membranes for use with larger protein products (typically ≤ 180 kD). They offer excellent virus retentive capabilities, and are consistently capable of protein recoveries exceeding 90%.

Each unit is 100% integrity tested during manufacturing by CorrTest to assure integrity.

Typical Applications

• Monoclonal antibodies including murine, human and hybrids
  
• Larger recombinant or transgenic proteins
  
• Larger plasma fractionation products

Typical Membrane Viral Retention (in Buffer)*

Dimensions