Tools for Detection of Tyrosine Phosphorylation
Overview:
Protein Tyrosine phosphorylation was first described in 1979. The development of the Anti-phosphotyrosine, clone 4G10® in 1989 was a monumental discovery for researchers. 4G10 was the first and best single monoclonal antibody for the detection of tyrosine phosphorylation. It is the most highly cited (75 % of related scientific journal articles over the last three years) and validated phosphotyrosine antibody available. It consistently produces high quality, reproducible data, and has been validated by thousands of scientific and medical researchers in virtually every application and tyrosine target over the past 18 years. In addition to its unparalleled characterization and applicability, 4G10 is well known as one of the most sensitive Anti-phosphotyrosines. Millipore now offers 4G10 Platinum, the new and improved phosphotyrosine antibody that blends clones 4G10 and PY20 to yield an antibody that takes the sensitivity for phosphotyrosine detection to the next level.
