OptiScale Capsule Filters for Clarification and Prefiltration Applications

Description

OptiScale capsules are a family of convenient, disposable filters ideal for media selection, process screening and scaling. These "drop-in" filter devices, with a variety of media options, create an effective platform for rapidly evaluating biopharmaceuticals. OptiScale offers speed-to-market strategies for efficiently developing compounds and biotherapeutics.

From benchtop to manufacturing, OptiScale capsules complement Millipore's extensive line of filters. They offer the same selection of media types as Millipore's process scale filters.

Typical Applications

OptiScale capsules are ideal for evaluating media to clarify biological feed streams such as cell cultures, serum, plasma and vaccines containing high levels of colloidal particles.

The capsules are also effective prefilters for fine chemicals and purified water processing.

Benefits

Scalable performance for speed-to-market
Innovative design offers convenience and efficiency
Faster than the 47 mm disc method
Disposable, reliable, easy-to-use
Choice of media optimizes your process development
Peel and stick label for easy tracking

Specifications

Materials of Construction
Structural Components	Polycarbonate
Filter Support	Polypropylene
Seal Ring	Fluoroelastomer
Vent Cap	PVDF
Chemistry
Durapore®	Hydrophilic PVDF
Milligard	Mixed Cellulose Esters
	Borosilicate Glass Fiber Mixed Cellulose Esters
Lifegard	Borosilicate Glass Fiber
	Polypropylene
Filtration Area, cm²	17.7
Maximum Operating Pressure, bar (psid)	5.5 (80) @ 25 °C
Bacterial Endotoxins	Aqueous extraction contains ≤0.25 EU/mL as determined by the Limulus Amebocyte Lysate (LAL) Test
Oxidizable Substances	Will meet the USP Oxidizable Substances Test requirements after a water flush of ≥100 mL
Component Material Toxicity	Component materials meet the criteria of the USP <88> Reactivity Test for Class VI Plastics. These products meet the requirements of the USP <88> Safety Test, utilizing a 0.9% sodium chloride extraction.
Sterilization
OptiScale with Durapore or Polygard-CN media	3 autoclave cycles of 60 min @ 126 °C; not in-line steam sterilizable
OptiScale with Milligard, Polysep II or Lifegard media	3 autoclave cycles of 60 min @ 121 °C; not in-line steam sterilizable
Indirect Food Additive	All component materials meet the FDA Indirect Food Additive requirements cited in 21 CFR 177-182.

Compare	Catalogue No.	Nominal Pore Size (µm)	Connections, Inlet/Outlet
	SGW1A47HH3	1.0 / 0.2 / 0.1	6 mm (1/4 in.) Hose Barb
	SGW1A47FH3	1.0 / 0.2 / 0.1	19 mm (3/4 in.) Sanitary Flange/6 mm (1/4 in.) Hose Barb
	SGW2A47FF3	1.0 / 1.2	19 mm (3/4 in.) Sanitary Flange
	SGW2A47FH3	1.0 / 1.2	19 mm (3/4 in.) Sanitary Flange/6 mm (1/4 in.) Hose Barb
	SGW2A47HH3	1.0 / 1.2	6 mm (1/4 in.) Hose Barb
	SGW3A47FF3	1.0 / 0.2	19 mm (3/4 in.) Sanitary Flange
	SGW3A47FH3	1.0 / 0.2	19 mm (3/4 in.) Sanitary Flange/6 mm (1/4 in.) Hose Barb
	SGW3A47HH3	1.0 / 0.2	6 mm (1/4 in.) Hose Barb
	SGW6A47FF3	1.0 / 0.5	19 mm (3/4 in.) Sanitary Flange
	SGW6A47FH3	1.0 / 0.5	19 mm (3/4 in.) Sanitary Flange/6 mm (1/4 in.) Hose Barb
	SGW6A47HH3	1.0 / 0.5	6 mm (1/4 in.) Hose Barb
	SGW9A47FF3	2.0 / 1.2	19 mm (3/4 in.) Sanitary Flange
	SGW9A47FH3	2.0 / 1.2	19 mm (3/4 in.) Sanitary Flange/6 mm (1/4 in.) Hose Barb
	SGW9A47HH3	2.0 / 1.2	6 mm (1/4 in.) Hose Barb

Compare	Catalogue No.	Nominal Pore Size (µm)	Connections, Inlet/Outlet
	SN03A47FF3	0.3	19 mm (3/4 in.) Sanitary Flange
	SN03A47FH3	0.3	19 mm (3/4 in.) Sanitary Flange/6 mm (1/4 in.) Hose Barb
	SN03A47HH3	0.3	6 mm (1/4 in.) Hose Barb
	SN06A47FF3	0.6	19 mm (3/4 in.) Sanitary Flange
	SN06A47FH3	0.6	19 mm (3/4 in.) Sanitary Flange/6 mm (1/4 in.) Hose Barb
	SN06A47HH3	0.6	6 mm (1/4 in.) Hose Barb
	SN12A47FF3	1.2	19 mm (3/4 in.) Sanitary Flange
	SN12A47FH3	1.2	19 mm (3/4 in.) Sanitary Flange/6 mm (1/4 in.) Hose Barb
	SN12A47HH3	1.2	6 mm (1/4 in.) Hose Barb
	SN1HA47FF3	10.0	19 mm (3/4 in.) Sanitary Flange
	SN1HA47FH3	10.0	19 mm (3/4 in.) Sanitary Flange/6 mm (1/4 in.) Hose Barb
	SN1HA47HH3	10.0	6 mm (1/4 in.) Hose Barb
	SN25A47FF3	2.5	19 mm (3/4 in.) Sanitary Flange
	SN25A47FH3	2.5	19 mm (3/4 in.) Sanitary Flange/6 mm (1/4 in.) Hose Barb
	SN25A47HH3	2.5	6 mm (1/4 in.) Hose Barb
	SN3HA47FF3	30.0	19 mm (3/4 in.) Sanitary Flange
	SN3HA47FH3	30.0	19 mm (3/4 in.) Sanitary Flange/6 mm (1/4 in.) Hose Barb
	SN3HA47HH3	30.0	6 mm (1/4 in.) Hose Barb
	SN50A47FF3	5.0	19 mm (3/4 in.) Sanitary Flange
	SN50A47FH3	5.0	19 mm (3/4 in.) Sanitary Flange/6 mm (1/4 in.) Hose Barb
	SN50A47HH3	5.0	6 mm (1/4 in.) Hose Barb

Compare	Catalogue No.	Nominal Pore Size (µm)	Connections, Inlet/Outlet
	SP15A47FF3	1.0	19 mm (3/4 in.) Sanitary Flange
	SP15A47FH3	1.0	19 mm (3/4 in.) Sanitary Flange/6 mm (1/4 in.) Hose Barb
	SP15A47HH3	1.0	6 mm (1/4 in.) Hose Barb
	SP20A47FF3	2.0	19 mm (3/4 in.) Sanitary Flange
	SP20A47FH3	2.0	19 mm (3/4 in.) Sanitary Flange/6 mm (1/4 in.) Hose Barb
	SP20A47HH3	2.0	6 mm (1/4 in.) Hose Barb

Compare	Catalogue No.	Nominal Pore Size (µm)	Connections, Inlet/Outlet
	SVHLA47FF3		19 mm (3/4 in.) Sanitary Flange
	SVHLA47FH3		19 mm (3/4 in.) Sanitary Flange/6 mm (1/4 in.) Hose Barb
	SVHLA47HH3		6 mm (1/4 in.) Hose Barb

Compare	Catalogue No.	Nominal Pore Size (µm)	Connections, Inlet/Outlet
	SW03A47FF3	0.2	19 mm (3/4 in.) Sanitary Flange
	SW03A47FH3	0.2	19 mm (3/4 in.) Sanitary Flange/6 mm (1/4 in.) Hose Barb
	SW03A47HH3	0.2	6 mm (1/4 in.) Hose Barb
	SW06A47FF3	0.5	19 mm (3/4 in.) Sanitary Flange
	SW06A47FH3	0.5	19 mm (3/4 in.) Sanitary Flange/6 mm (1/4 in.) Hose Barb
	SW06A47HH3	0.5	6 mm (1/4 in.) Hose Barb
	SW19A47FF3	1.2	19 mm (3/4 in.) Sanitary Flange
	SW19A47FH3	1.2	19 mm (3/4 in.) Sanitary Flange/6 mm (1/4 in.) Hose Barb
	SW19A47HH3	1.2	6 mm (1/4 in.) Hose Barb
	SWSCA47FF3	1.2 / 0.5	19 mm (3/4 in.) Sanitary Flange
	SWSCA47FH3	1.2 / 0.5	19 mm (3/4 in.) Sanitary Flange/6 mm (1/4 in.) Hose Barb
	SWSCA47HH3	1.2 / 0.5	6 mm (1/4 in.) Hose Barb
	SWSSA47FF3	0.5 / 0.2	19 mm (3/4 in.) Sanitary Flange
	SWSSA47FH3	0.5 / 0.2	19 mm (3/4 in.) Sanitary Flange/6 mm (1/4 in.) Hose Barb
	SWSSA47HH3	0.5 / 0.2	6 mm (1/4 in.) Hose Barb

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