Pellicon 2 Microfiltration Cassettes

The Pellicon 2 product line was designed with process scale-up and applications development in mind. The series of devices includes the long established Durapore hydrophilic PVDF microfiltration membrane, well known for its exceptional combination of high flux, low protein binding and high product recoveries.

Benefits

Leading-edge void-free membranes to match virtually any separation challenge
Short flow path for higher flux and higher resolution separation capability
Choice of flow channel conﬁguration providing process optimization capability
Predictable, fast, scale-up
True linear scalability from laboratory size modules to industrial assemblies for processing thousands of liters

Applications

Clarification – of protein solutions, polysaccharide solutions, virus suspensions/cultures, cell lysates and pre-column streams
Harvesting – of cell cultures and colloidal suspensions
Harvesting and Washing – of colloidal suspensions, bacterial cells or viral cultures

Pellicon 2 Filters and Holders

Normalized Recirculation Rates
Parameter	Unit	Typical ∆P
Screen Type	N/A	A C V
Recirculation Rate	L/min/m²	4/6 5/35
Differential Pressure	bar/psi	1.4/20 0.4/6

Screen Selection Guidelines
Solution Type	Screen Type
Dilute protein solution or low viscosity solutions (mAbs, interferons)	A screen (tight screen)
Concentrated protein solutions or high viscosity solutions (IgG, biopolymers)	C screen (coarse screen)
High viscosity solutions (polysaccharides, certain microfiltration or clarification applications)	V screen (loose screen)

Specifications
Temperature Range
Mini, Cassette and Maxi:	4 to 50 °C
Prefiltration Required
Mini, Cassette and Maxi:	100 µm
Dimensions
Device	Width	Length	Thickness
Mini	5.6 cm	21 cm	1.5 cm (V screen-2.16 cm)
Cassette	17.8 cm	21 cm	1.5 cm (V screen-2.16 cm)
Maxi	17.8 cm	21 cm	7.6 cm (V screen-9.0 cm)

Membrane Selection Chart
Durapore Membranes
Approximate Molecular Weight (range of solutes retained > 99%, kD)	Membrane	NMWL (kD) or Microns	Membrane Material	pH Range
Clarify cell lysates and protein solutions, clarify viral cultures	VVPP	0.1 µm	Hydrophilic PVDF	2 – 11
Harvest & wash colloidal suspensions, bacterial cells; clarify protein solutions and viral cultures	GVPP	0.22 µm	Hydrophilic PVDF	2 – 11
Harvest & wash colloidal suspensions, cell & viral cultures; clarify protein solutions & viral cultures	HVMP	0.45 µm	Hydrophilic PVDF	2 – 11
Harvest cell cultures or colloidal suspensions	DVPP	0.65 µm	Hydrophilic PVDF	2 – 11

Ordering Information

Select up to 5 products to compare them side by side

Mini · C Screen

Top »

Compare	Catalogue No.	Filter Code	Pore Size (µm)
	P2VVPPC01	VVPP	0.1
	P2GVPPC01	GVPP	0.22
	P2HVMPC01	HVMP	0.45
	P2DVPPC01	DVPP	0.65

Mini · V Screen

Top »

Compare	Catalogue No.	Filter Code	Pore Size (µm)
	P2VVPPV01	VVPP	0.1
	P2GVPPV01	GVPP	0.22
	P2HVMPV01	HVMP	0.45
	P2DVPPV01	DVPP	0.65

Cassette · C Screen

Top »

Compare	Catalogue No.	Filter Code	Pore Size (µm)
	P2VVPPC05	VVPP	0.1
	P2GVPPC05	GVPP	0.22
	P2HVMPC05	HVMP	0.45
	P2DVPPC05	DVPP	0.65

Cassette · V Screen

Top »

Compare	Catalogue No.	Filter Code	Pore Size (µm)
	P2VVPPV05	VVPP	0.1
	P2GVPPV05	GVPP	0.22
	P2HVMPV05	HVMP	0.45
	P2DVPPV05	DVPP	0.65

Maxicassette · C Screen

Top »

Compare	Catalogue No.	Filter Code	Pore Size (µm)
	P2VVPPC25	VVPP	0.1
	P2GVPPC25	GVPP	0.22
	P2HVMPC25	HVMP	0.45

Maxicassette · V Screen

Top »

Compare	Catalogue No.	Filter Code	Pore Size (µm)
	P2VVPPV20	VVPP	0.1
	P2GVPPV20	GVPP	0.22
	P2HVMPV20	HVMP	0.45
	P2DVPPV20	DVPP	0.65

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Pellicon 2 Microfiltration Cassettes

Benefits

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Ordering Information

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