Cogent M1 TFF System
The Cogent M1 system is an easy-to-use bench-top TFF system
that is ideally suited for process development, scaling studies, as well as
clinical trials and small-scale production. An innovative and intelligent
design, the system enables an extremely low hold-up volume for maximum volume
concentration and optimal product recovery.
Equipped with a 10-liter
tank with embedded balance, the Cogent M1 system can also runin fed-batch or
diafilitration mode using an optional transfer pump, which enables the system
to process up to 100 liters or more based on product and membrane filter
characteristics.
Benefits
- Extremely low hold up volume for
maximum product recovery
- Enhanced productivity
- Easy-to-use
- Can process up to 100 liters or more
| Specifications | |
| Supported TFF Devices | |
| Pellicon 2 (0.1 m²) cassettes: | Up to 5 (0.1 m² to 0.5 m² ) |
| Pellicon 2 (0.5 m²) cassettes: | Up to 2 (0.5 m² to 1.0 m² )* |
| Pellicon 3 (0.11 m²) cassettes: | Up to 4 (0.11 m2 to 0.44 m2) |
| Pellicon 3 (0.57 m²) cassettes: | Up to 2 (0.57m² to 1.14 m² )* |
| Pellicon Cassette Holder Included with System | Holds up to four Pellicon 3 (0.11 m²) cassettes Holds up to five Pellicon 2 (0.1 m²) cassettes |
| Pellicon Cassette Labscale Holder | Holds up to two Pellicon 3 (0.57 m²) cassettes Holds up to two Pellicon 2 (0.5 m²) cassettes |
| Filtration Area | 0.1 m² to 1.14 m² |
| Minimum Working Volume | 300 mL at 20% feed pump speed |
| Starting Volume | Tank volume of 10 liters |
| Hold-up Volume | < 10 mL (excluding cassette) |
| Process Temperature Range | 4 ºC to 50 ºC (39 °F to 122 °F) |
| Maximum Feed Flowrate | 4.5 L/min at 5 bar g (72.5 psi) |
| Minimum Feed Flowrate | 200 mL/min |
| Maximum Operating Pressure | 5 bar g (72.5 psi) |
| Maximum System Pressure | 6 bar g (86 psi) before pump shut-off |
| Optional Transfer Pump Flowrate | Tubing dependant (0.16 to 2300 mL/mn) |
| Languages Supported | English, French, German, Spanish, Italian, Chinese and Japanese |
| Dimensions | |
| Width: | 76.8 cm (30.23 in.) |
| Depth: | 51.2 cm (20.16 in.) |
| Height: | 114.7 cm (45.16 in.) |
| Weight | Approximately 78kg (172 lbs) |
| Wetted Materials of Construction | |
| Ferrous parts: | 316L stainless steel (with Material certificates) |
| Polymers (USP Class VI or FDA): | EPDM, Santoprène® elastomer, medical grade epoxy, silicone |
| Supply Voltage | |
| Europe, UK, China: | 220 – 230 VAC, 50 or 60 Hz, 1-phase |
| North America, Japan: | 100 – 120 VAC, 50 or 60 Hz, 1-phase |
| Regulatory Information | The Cogent M1 system meets the require- ments of the Low Voltage Directive 73/23/ EEC and the EMC Directive 89/336/EEC, and is CE marked. |
| *The specified items are optional. Note: Maximum area depends on application fluid and flow characteristic. |
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