Milligard Cartridge Filters

Description

Milligard cartridge filters provide the finest prefiltration available. Milligard filters are constructed of homogeneous polymers of cellulose esters on a polyester web resulting in a versatile filter with high reproducibility and efficacy due to the highly retentive, non-fiber releasing membrane. The homogenous cellulose ester membrane provides the high retention needed during critical prefiltration steps while protecting more expensive downstream filtration devices from premature plugging.

Milligard filters are available in single and double layer formats, as well as a special low protein binding version constructed of low protein binding cellulose esters that is designed for the removal of particles and microorganisms in applications where maximizing protein recovery is critical.

Milligard cartridge filters provide high throughput with minimal differential pressure. Cartridges are robust, strong, resilient and are designed to withstand multiple steam-in-place cycles. Milligard cartridge filters are integrity tested during the manufacturing process.

Regulatory Compliance

Milligard cartridge filters are designed, developed, and manufactured in accordance with a Quality Management System approved by an accredited registering body to an ISO® 9000 Quality Systems Standard and are shipped with a Certificate of Quality. Each cartridge filter is supported by a Validation Guide for compliance with regulatory requirements.

For traceability and easy identification, each filter is marked with identifying characteristics.

Multiple Format

A full range of filtration areas is available to suit varying application requirements. A variety of connection options are offered for easy adaptation to existing housings.

Typical Applications

Cell Culture Media
Effectively remove particles and colloidal contaminants without obstructing the flow of vital media constituents. Milligard prefilters provide the high flow rates and consistently high throughput required to accomplish the separation in a timely and cost-effective manner.
Final Aseptic Fill of Small Volume Parenterals (SVP)
Extend the service life of downstream sterilizing filters by removing colloidal and particulate contaminants.
Large Volume Parenterals (LVP)
Extend the service life of downstream sterilizing filters by removing colloidal and particulate contaminants. Extremely robust and able to withstand high operating pressures, Milligard filters offer dependable retention and high flow rates needed for high volume manufacturing.
Plasma Proteins—Human Albumin
Remove colloids, aggregated and non-product proteins, lipids and particles prior to downstream purification without retaining the fractions of interest. Milligard filters provide superior protection of downstream sterile filters and/or chromatography columns.
Serum
Effectively remove lipids, colloids, and particles from serum before the final sterilizing filtration without obstructing the passage of serum proteins. Milligard filters provide high flow rates and consistently high throughput.

Specifications (return to top)

Typical Clean Water Flow Rate vs Pressure Drop

Cartridge Legends Refer to Pore Size (nominal):
Milligard Media
CW03 = 0.2 µm
CW06 = 0.5 µm
CW19 = 1.2 µm
CWSC = 1.2/0.5 µm
CWSS = 0.5/0.2 µm
Milligard LPB Media
CWL3 = 0.2 µm
CWL6 = 0.5 µm
CWL9 = 1.2 µm
CWLC = 1.2/0.5 µm
CWLS = 0.5/0.2 µm

Cartridges with Milligard Media - 30-inch, Cartridge Code 0

Cartridge with Milligard LPB Media - 30-inch, Cartridge Code 0