Millistak+® CE Stacked Disc Filters
Description
Millistak+® clarification/prefiltration stacked disc
filters have been specifically developed to meet the critical needs of the
pharmaceutical and biotech industries, incorporating a broad range of
controlled porosity graded density depth media.
Available media
series satisfy most applications needs in the biopharmaceutical market where
high concentrations of colloidal contaminant dictate the need for high surface
area depth media with a positive charge. Within the CE series, a variety of
grades enable the user to choose the filter best suited to his application.
Media grades are differentiated by flow characteristics rather than by micron
ratings. Nominal retention guidelines are provided but trials in customer
fluids are recommended for selection of the optimum filter based on processing
conditions. The CE series is suitable for coarse filtration in the 1 to 30
micron range.
Benefits
- Monitored gradient density matrix
assures consistent filtration performance
- Filter matrix exhibits
positive charge properties to enhance filtration performance
- Broad
range of media grades to assure optimal performance
- Non-toxic
- Media available to fit virtually any filter press
Extractables
Typical extractable levels have been determined by laboratory analysis utilizing a dynamic flow rinse procedure. Inorganic extractables are quantified by atomic absorption analytical techniques. The results are expressed as milligram per ft2 of media subsequent to the standard recommended flush of 100 L/m2 (10 L/ft2) of media surface area.
| Metal | mg/ft2 Media |
| Sodium | 3.45 - 4.76 |
| Calcium | 2.56 - 2.74 |
| Potassium | 0.17 - 0.91 |
| Magnesium | 1.19 - 2.03 |
| Iron | <0.1 |
| Lead | <0.1 |
| Aluminum | <0.1 |
| Titanium | <0.1 |
| Chromium | <0.1 |
| Manganese | <0.1 |
| Cobalt | <0.1 |
| Nickel | <0.1 |
| Copper | <0.1 |
| Zinc | <0.1 |
Dimensions
| Materials of Construction | |
| Filter Media | Cellulose |
| Structural Components | Polypropylene |
| Maximum Differential Pressure, bar (psid) | Forward: 2.07 (30) @ 25 °C; 1.03 (15) @ 80 ° C |
| Bacterial Endotoxins | Aqueous extraction contains <0.25 EU/mL as determined by the Limulus Amebocyte Lysate (LAL) clot test technique |
| Component Material Toxicity | Component materials meet the criteria of the USP <88> Reactivity Test for Class VI Plastics. These products meet the requirements of the USP <88> Safety Test, utilizing a 0.9% sodium chloride extraction. |
| Oxidizable Substances | The effluent of an autoclaved (1 cycle of 30 minutes @ 123 °C) stacked device is negative after a WFI flush of 10 liters per ft2 (100 L/m2) of media surface area |
| Indirect Food Additive | All component materials meet the FDA Indirect Food Additive requirements cited in 21 CFR 177-182. |
| Sterilization | May be steam sterilized for 3 steam-in-place (SIP) cycles of 30 minutes @ 123 °C |
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