Viresolve® Pro and Pro+ Solutions

Robust parvovirus clearance

• ≥ 4 log removal of parvovirus
  
• Devices are 100% tested with air/water diffusion and Millipore patented Binary Gas Test

Enables high productivity virus filtration unit operation

• High mass capacity
  
• Optional capacity enhancement with use of adsorptive polishing step
  
• Less than 4-hour processing at scale
  
• Disposable flow path at all scales requiring no cleaning validation
  
• Caustic stable
  
• Easy to install, use and integrity test

Next generation solution from a company with proven expertise and user support

The Viresolve Pro solution is based on an innovative, dual layer PES membrane and device that was designed to simultaneously deliver high parvovirus LRV, capacity and flux. The Viresolve Pro+ solution includes the shield in-line with the device enabling increased process robustness and high productivity as well as high parvovirus LRV, capacity and flux. The new shield and device formats are designed to fit your process and enable productivity gains from process development to full-scale production. All of the shield and device formats are fully disposable and are caustic stable for optional in situ sanitization. Viresolve Pro and Pro+ Modus shields and devices can be used at pilot scale as part of the Mobius® FlexReady virus filtration solution.

Viresolve Pro membrane and devices undergo comprehensive performance and integrity tests to ensure quality and consistency.

With over 20 years of virus filtration experience, our application, process development, and virology experts are available to help you implement the Viresolve Pro and Pro+ Solutions into your process. Our range of Virus Safety services will assist you as you progress through your process development, validation and full scale processing, helping you reach your process economics and performance goals efficiently.

Device Family Overview

Viresolve Pro PD Kit

• Viresolve Pro Micro devices for process development, optimization and scale-up
  
• Not Binary Gas Tested
  
• Nine devices from one membrane layering combination
  
• Air vent to prevent air locking

Viresolve Pro Val Kit

• Viresolve Pro Micro devices for virus validation studies
  
• Binary Gas Tested
  
• Three devices from three different membrane layering combinations
  
• Air vent to prevent air locking

Viresolve Pro+ PD Kit

Viresolve Pro Micro shields and devices for process development, optimization and scale-up
• Nine shields and devices from one membrane layering combination
• Air vent to prevent air locking

Viresolve Pro+ Val Kit

Viresolve Pro Micro shields and devices for virus validation studies
• Nine shields from one membrane layering combination
• Three devices from three different membrane layering combinations
• Air vent to prevent air locking

Viresolve Pro Modus Shields and Devices

• Pilot and medium volume processing
  
• Three device sizes
  
• Fully self contained (requiring no holder)
  
• Devices are 100% tested with air/water diffusion and Binary Gas Test
  
• Shields are 100% aerosol tested

Viresolve Pro Magnus Shields and Devices

• Large volume processing
  
• Integrated gaskets
  
• Alignment keys to minimize errors during installation
  
• Fully disposable fluid path – holder has no product contact
  
• Low hold up volume (proportional to the installation area)
  
• Devices are 100% tested with air/water diffusion and Binary Gas Test
  
• Shields are 100% aerosol tested

Viresolve Pro Holder and Accessories

• No product contact – eliminates need for cleaning validation
  
• Ergonomic and easy-to-clean design to fit into your facility
  
• Vertical orientation to minimize holder footprint
  
• Rods in multiple lengths for various size installations
  
• Simple manual hydraulics

Regulatory Compliance and Supporting Documentation Package

• Validation Guide, Certificates of Quality, and User Guides