LC-Pak

Recent advances in analytical techniques such as UPLC, LC-MS, LC-MS / MS have considerably improved the sensitivity of organic and biochemical molecules detection. As a result, these techniques require now improved water quality for the production of mobile phase, buffers, blanks, standards preparation, sample dilution, glassware rinsing or extraction.

Although fresh Milli-Q water quality has remained so far adequate for most procedures involving these advanced techniques, a need has recently appeared for higher water quality in some advanced applications.

To answer this emerging need, Millipore has developed a new POD-Pak designed to produce ultrapure water with an organics contamination level below most water sources available today, at a fraction of the cost.

The LC-Pak can be connected to the outlet of existing and new Millipore Type 1 water systems (Milli-Q, Direct-Q, Synergy and Simplicity) producing ultrapure water with a TOC level below 5 ppb, in order to deliver at least 500 L of ultrapure water with minimum trace organic contamination, using as a purification media the well known C18 reverse phase silica to remove traces of organics.

The LC-Pak is designed to provide scientists with the certitude that the ultrapure water that they are using in critical organic molecules analysis at trace and ultra-trace levels will be adequate.

The granular C18 reverse phase silica in the polypropylene housing is tightly packed by a compression disc to avoid any channeling effect. This ensures that the water passing through the LC-Pak will be in close contact with the C18 chains binding organic molecules by hydrophobic interactions.