Proteins
We offer a variety of proteins for your cell biology research needs. Our matrix metalloproteinases (MMP’s) and tissue inhibitors of metalloproteinases (TIMPs) are highly purified for use as positive controls and in activity studies. The balance between these proteins plays a critical role in tissue remodeling, wound healing, angiogenesis, and tumorogenesis.
In the same family are our ADAM proteins (A Disintegrin And Metalloproteinase), cell surface markers whose biological functions have not entirely been determined. Integrins are also closely related, and we offer a wide selection for your research on adhesion and cellular function.
Metalloproteinases (MMPs)
Matrix metalloproteinases (MMPs) represent a family of 20+ members of secreted or transmembrane bound proteolytic endopeptidases that require zinc ions for their enzymatic activity and share particular structural similarities...
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Tissue Inhibitors of Metalloproteinases (TIMPs)
Tissue inhibitors of metalloproteinases (TIMPs) are natural inhibitors of matrix metalloproteinases (MMPs) found in most tissues and body fluids...
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A Disintegrin and Metalloproteinase (ADAM)
ADAM proteins are members of the same superfamily as MMPs, namely the Metzincins, named for their zinc binding domains and their structurally important C-terminal conserved methionine residue...
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Integrins & Extracellular Matrix
Cell adhesion plays a major role in cell communication and regulation and is of fundamental importance in the development and maintenance of tissues...
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Integrin Arrays
Identification of cellular integrin profiles and ECM binding properties is the first step in understanding the mechanism of action in cell-ECM interactions...
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Pathways
