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Millipore Expands Collection of Lipid Kinases

Billerica, Massachusetts—November 20, 2007—Millipore Corporation, a Life Science leader providing technologies, tools and services for the bioscience research and biopharmaceutical manufacturing industry, today announced the expansion of its PI3 kinase line, making it the broadest panel of lipid kinases available worldwide. Millipore now offers 17 lipid kinases, available both for purchase and as part of its gold-standard KinaseProfiler™ service. No other company provides this many kinases.

Lipid kinases are one of the most promising new classes of potential drug targets. PI3 kinases regulate a wide variety of cellular functions, including cell growth, proliferation, differentiation, motility, survival, and intracellular trafficking. As a result, defects in PI3 kinase function lead to multiple disease states, including several forms of cancer. Millipore’s newly-expanded lipid kinase panel and KinaseProfiler service provide the tools to dissect the networks underlying PI3 kinase signaling, essential to the design of new therapies.

Combined with Millipore’s industry-leading PI3 Kinase HTRF™ Assay, KinaseProfiler service, and small-molecule inhibitors, the expanded lipid kinase panel provides researchers with the most complete solution to studying lipid kinase signaling. The new lipid kinase panel includes both wild type and disease-linked mutants.

Established in 1954 as a high performance filtration products and services company, Millipore has grown into a partner for Life Science customers through R&D investment, organic growth and acquisitions. Companies acquired include Chemicon®, Upstate®, Linco®, and NovaSeptic® AB. . The integrated Millipore offers you more innovative technologies and stronger application support to streamline your progress and give you more confidence in your results. Our target profiling services, multiplex and traditional immunoassays and clinical lab contract services help our customers prioritize potential drug candidates, screen many biomarkers simultaneously, and conduct research and clinical studies.