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Millipore Launches Tyrosine Kinases with BioForm™ Technology

Billerica, Massachusetts—December 17, 2007—Millipore Corporation, a Life Science leader providing technologies, tools and services for the bioscience research and biopharmaceutical manufacturing industry, today announced the launch of its Tyrosine Kinases with BioForm Technology developed by P.A. Technologies in Amherst, MA. The coupling of the technology and select Millipore Tyrosine kinases provides a better, more biologically relevant environment for cell signaling research and discovery efforts.

Conventional analysis of membrane protein signaling involves studying a single protein interacting with a single partner. Such analysis loses rich, two-dimensional information afforded by organization of proteins on the membrane surface. BioForm Technology enables the unique assembly of histidine-tagged proteins in an environment that mimics that created by a cell membrane. This template restores the organizing features of the membrane without the difficulties of membrane preparation and reconstruction procedures. The technology is adaptable to high throughput assay format and is applicable to many signaling systems.

Millipore’s Tyrosine Kinases with BioForm Technology can be used in many key stages of drug discovery research, including early stage drug screening, signal transduction and regulation of enzymatic activity. Additionally, this new kinase assay platform may be used for functional in vitro assembly of multiple protein targets.



Established in 1954 as a high performance filtration products and services company, Millipore has grown into a partner for Life Science customers through R&D investment, organic growth and acquisitions. Companies acquired include Chemicon®, Upstate®, Linco® and NovAseptic® AB. The integrated Millipore offers you more innovative technologies and stronger application support to streamline your progress and give you more confidence in your results. Our target profiling services, multiplex and traditional immunoassays and clinical lab contract services help our customers prioritize potential drug candidates, screen many biomarkers simultaneously, and conduct research and clinical studies.

About Millipore
Millipore (NYSE: MIL) is a Life Science leader providing cutting-edge technologies, tools, and services for bioscience research and biopharmaceutical manufacturing. As a strategic partner, we collaborate with customers to confront the world’s challenging human health issues. From research to development to production, our scientific expertise and innovative solutions help customers tackle their most complex problems and achieve their goals. Millipore Corporation is an S&P 500 company with more than 6,100 employees in 47 countries worldwide.

ADVANCING LIFE SCIENCE TOGETHER™
Research. Development. Production.


Millipore, Chemicon, Upstate, Linco and NovAseptic are registered trademarks and BioForm, the “M” logo ADVANCING LIFE SCIENCE TOGETHER are trademarks of Millipore Corporation.

All other trademarks are the property of their respective corporations.


Media Contact:
Lauren Nolan
Marketing Communications
Millipore Corporation
871-762-5080
lauren_nolan@millipore.com

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