Monoclonal Antibodies
- In vitro or in vivo production of murine and human hybridomas
- Antibody production in static, roller, airlift, perfusion, Wave™ and stirred systems
- Fermentation volumes from 1 L – 5,000 L
Protein Expression
- E. coli
- Insect cells
- Protein production in static, roller, airlift, Wave™ and stirred systems
- Fermentation volumes from 1 L – 100 L
Conjugation: Antibodies and Proteins
- FITC
- Rhodamine
- DTAF
- Biotin
Filling and Packaging
- Dedicated multi-product, class 10,000 clean room able to handle bulk volumes for sterile filtration and dispensing
- Class 100 contained multi-filling systems for container sizes 1 mL – 100L Biocontainers
- Flexible primary packaging and kit formatting
Cell Line Optimization and Storage
- Serum-free adaptation for improved yields and ease of purification
- cGMP cell banking and inventory management
Polyclonal Antibodies
- Antigen development from native, recombinant and synthesized sources
- Goats, sheep, rabbits, mice and other species available
- Standard or custom immunization protocols
- Small to large scale serum processing
Purification
- Protein A or G
- Ammonium sulphate
- Affinity
- Client dedicated columns
- Ion Exchange
- Hydrophobic Interaction Chromatography (HIC)
- Size Exclusion
Custom
- Formulation of bulk reagents
- Blocking reagents for interfering antibodies
- Functional and purity assays to your specifications
- Peroxidase
- Photoproteins
- Alkaline Phosphatase
Take advantage of our:
- Project and production management of multiple products and cell lines
- Flexibility in scale and processes
- Dedicated quarantine and development facilities
- Validated disposable technology for production integrity
- Quality and Regulatory Support including:
- FDA CBER Licensed Biologic Facility compliant with FDA 21 CFR 600 and FDA 21 CFR 820
- ISO 9001:2000, ISO 13485:2003, IVD98-79-EC and CMDCAS certifications