dCTP and CTP Nucleotides
Millipore’s dCTP and CTP nucleotides are ideal for labeling DNA using PCR*, Nick Translation or Random Priming methods. Our proprietary nucleotide* is conjugated to a number of reporter molecules and is available in convenient 1 mM solutions or in bulk quantities for further manufacturing purposes. Samples for testing are available.
- Convenient
Labeled nucleotides available in bulk quantities for further manufacturing uses
- Practical
Ideal for commercial probe manufacture and as a kit component
- Cost-effective
Avoid costly licenses with use of this patented chemistry and proprietary linker
Post-Amplification, Nucleic Acid Detection
Millipore’s OligoDetect assays for highly-sensitive detection of post-amplification products are suitable for large scale screening. The OligoDetect system employs a simple 96-well immunoassay format designed to detect specific biotinylated nucleic acid products. The biotin-labeled, amplified DNA sample is captured on a specific probe-coated plate. The captured amplicon is detected with a streptavidin conjugate. Millipore will work with you to design custom primers, hybridization controls, and assay plates. This rapid, non-isotopic method of amplified nucleic acid detection eliminates the need for gel electrophoresis and Southern blots, ofÂfering significantly better detection sensitivity. The 96-well OligoDetect assay format is suitable for automated and high throughput systems. Results are available in approximately 60 minutes. Large custom lots may be archived for rapid reorder and reagent consistency.
*OBEA-dCTP and OBEA-CTP are derivatized nucleotides at the N4 position of dCTP and CTP, respectively, to which different labels (Biotin, Fluorescein, Sulforhodamine, DNP, and Rhodamine Green™, and other custom dyes) are covalently attached. Millipore has a unique, proprietary position or derivatization of dCTP and CTP at N4, and on the linker (OBEA, oxy-bis-ethylamine) under US Patent 5,684,142. All nucleotides are supplied at a concentration of 1.0 mM as a TEA salt.
