GPCR Products
Ready-to-Assay Cell Lines and Membranes
We are continually striving to develop innovative products for GPCR research. Our Ready-to-Assay product line accelerates GPCR drug discovery by providing convenience for routine drug assays.» View Product Listing - Ready-to-Assay Cell Lines
» View Product Listing - Ready-to-Assay Membranes
Ready-to-Assay GPCR Calcium-Optimized Cells
Ready-to-Assay Cells are an ultra convenient, cryopreserved version of our ChemiScreen GPCR Calcium-Optimized cell lines. Our assay cells eliminate the aggravation of extensive tissue culture required for traditional cell lines while speeding up assay completion. Thaw. Plate cells. And run your experiment - all within 24 hours.Features
- Cell-based assays within 24 hrs from start to finish
- Cryopreserved version of ChemiScreen Calcium-Optimized GPCR Cell Lines
- High cellular viability and assay signal
- Preserved pharmacology
- Available in bulk quantities
Comparison of Potency and Efficacy of Ready-to-Assay GPCR Calcium-Optimized Cells Versus Traditional Continuously Passaged ChemiScreen GPCR Calcium-Optimized Stable Cell Lines By Ca2+ Flux Assay
Product Listing: Ready to Assay Cell Lines
A | non-peptide | Adrenergic | alpha1A | Chem-1 | ||
A | non-peptide | Adrenergic | beta 1 | Chem-1 |  | |
A | non-peptide | Adrenergic | beta 2 | Chem-1 | | |
A | non-peptide | Adrenergic | beta 3 | Chem-10 | | |
A | non-peptide | Cannabinoid | CB1 | Chem-1 | | |
A | non-peptide | Cannabinoid | CB2 | Chem-4 | | |
A | peptide | Chemokine | CCR1 | Chem-1 | | |
A | peptide | Chemokine | CCR2B | Chem-1 | | |
A | peptide | Chemokine | CCR4 | Chem-5 | | |
A | peptide | Chemokine | CCR9 | Chem-1 | | |
A | peptide | Chemokine | CXCR1 / IL-8a | Chem-1 | | |
A | peptide | Chemokine | CXCR2 / IL-8b | Chem-1 | ||
A | peptide | Chemokine | CXCR3 | Chem-1 | | |
A | peptide | Chemokine | CXCR4 | Chem-1 | | |
B | peptide | CRF Receptor | CRF1 | Chem-1 | | |
B | peptide | CRF Receptor | CRF2 | Chem-1 | | |
A | non-peptide | Free Fatty Acid | FFA3 / GPR41 | Chem-4 | | |
A | non-peptide | Free Fatty Acid | FFA2 / GPR43 | Chem-1 | | |
B | peptide | Glucagon | GIP | Chem-9 | | |
B | peptide | Glucagon | glucagon / GCG | Chem-1 | ||
B | peptide | Glucagon | secretin receptor / SEC | Chem-1 | | |
C | non-peptide | Glutamate (metabotropic) | mGlu2 | Chem-1 | | |
A | non-peptide | Leukotriene | BLT1 | Chem-1 | | |
A | non-peptide | Leukotriene | CysLT1 | Chem-1 | | |
A | non-peptide | Lysophospholipid | LPA3 / EDG7 | Chem-1 | | |
A | non-peptide | Lysophospholipid | S1P1 / EDG1 | Chem-4 | | |
A | non-peptide | Lysophospholipid | S1P2 / EDG5 | Chem-1 | | |
A | non-peptide | Lysophospholipid | S1P3 / EDG3 | Chem-1 | | |
A | non-peptide | Lysophospholipid | S1P4 / EDG6 | Chem-5 | | |
A | peptide | Neuropeptide Y | Y2 | Chem-1 | | |
A | peptide | Neurotensin | NTR1 / NTS1 | Chem-1 | | |
A | peptide | N-formylpeptide | FPRL1 / AXL / HM63 | Chem-1 | | |
A | peptide | Orexin | OX1 | Chem-1 | | |
A | peptide | Orexin | OX2 | Chem-1 | | |
A | non-peptide | Prostanoid | DP | Chem-1 | | |
A | non-peptide | Prostanoid | EP1 | Chem-1 | | |
A | non-peptide | Prostanoid | EP2 | Chem-9 | | |
A | non-peptide | Prostanoid | EP3 | Chem-1 | | |
A | non-peptide | Prostanoid | EP4 | Chem-1 | | |
A | non-peptide | Prostanoid | FP | Chem-1 | | |
A | non-peptide | Prostanoid | IP1 / PGI2 | Chem-1 | | |
A | non-peptide | Prostanoid | TP / TXA2 / PGH2 | Chem-1 | | |
B | peptide | PTH receptor | PTH1 | Chem-1 | | |
B | peptide | PTH receptor | PTH2 | Chem-1 | | |
B | peptide | VIP/PACAP | VPAC1 / VIP1 | Chem-1 | | |
| | Control | Chem-1 | CHEM-1 PARENTAL CELL LINE | |
Ready-to-Assay Pre-Plated Membranes
Ready-to-Assay Pre-Plated Membranes combine our GPCR membrane preparations and MultiScreenHTS glass-fiber filtration plates into a single product. This simplifies binding assays and increases throughput. Membranes, at 1 unit per well, are spotted onto MultiScreenHTS plates and frozen. This allows you to thaw the plate, add the assay mixture, and after the reaction equilibrates, filtration can be performed directly on the assay plate. Millipore offers two Ready-to-Assay Pre-Plated Membrane formats: 1) single receptor per plate or 2) plate spotted with multiple receptor family members to further simply selectivity profiling.Features
- Millipore GPCR membranes pre-aliquoted onto assay plates
- Reduced steps compared to traditional filtration
- Single plate for both assay & filtration
- Amenable to automation
- High signal-to-noise
- Available in bulk quantities
Comparison of Affinity and Total Binding of Ready-to-Assay Pre-plated GPCR Membrane Preparations Versus Conventional Filtration Assays Using ChemiScreen GPCR Membrane Preparations. | |
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Product Listing: Ready to Assay Pre-plated Membranes
| A | non-peptide | Adrenergic | alpha1A | Chem-1 | |
| A | non-peptide | Adrenergic | beta 1 | Chem-1 | |
| A | non-peptide | Adrenergic | beta 2 | Chem-2 | |
| A | non-peptide | Adrenergic | beta 3 | Chem-1 | |
| A | non-peptide | Prostanoid | CRTH2 / DP2 / GPR44 | Chem-1 | |
| A | non-peptide | Prostanoid | EP2 | Chem-1 | |
| A | non-peptide | Prostanoid | EP3 | Chem-1 | |
| A | non-peptide | Prostanoid | EP4 | Chem-1 | |
| A | non-peptide | Prostanoid | TP / TXA2 / PGH2 | Chem-1 | |
| A | non-peptide | Prostanoid | DP2, DP, EP3, EP4, TP |
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Novità & lancio di nuovi prodotti
- As GPCR Space Becomes More Crowded, Drug Makers Show Affinity for Non-traditional GPCR Binding Sites
- Millipore Corporation and CXR Biosciences Introduce Toxicity Reporter Assay Panel
- Millipore Launches MILLIPLEX™ MAP
- Millipore Announces Stem Cell Tested Initiative
Prodotti in vetrina
