PathwayProfiler Service

Millipore’s world leading expertise in phospho-specific antibodies and the power of multiplex assays based on the Luminex xMAP platform offer you an unimpeded view into cellular response. PathwayProfiler is a convenient, time-saving service for the simultaneous investigation of customer-defined signal transduction events in a native cellular environment.

PathwayProfiler can be employed to screen protein modifications of off-target signaling pathways or to develop a more complete biological understanding of in vivo compound efficacy in a wide variety of cellular environments. In addition, the ability to combine our PathwayProfiler and KinaseProfiler services enables our customers to determine relationships between specific kinases and complex signal transduction pathways.

Simply prepare your cell lysates, choose your targets (total and phosphorylated) and leave the rest to Millipore’s BioMarker Services Team. Samples and controls are handled and analyzed by highly trained technicians, following strict protocols with precision and reliability. Customers receive a report with protein and phosphoprotein levels for each sample provided. The report also includes raw data, normalized data and complete quality control information.

Features of PathwayProfiler Service:

• Cell-based assays
• Multiplexed phospho-specific readout
• Drug testing in physiological conditions
• Precise & reliable results
• User customizable

Advantages of PathwayProfiler Service:

• Small sample volumes accepted
• Consistent quality control
• Expertise in high quality sample analyses
• Guaranteed reproducibility
• Prompt & flexible reporting
• Leader in multiplex services – intracellular & extracellular
• Long & proven history successful collaborations with clients
• Two- to four-week turnaround time (depending on size & complexity of project)