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Reference Data

Defining Selectivity Signatures of Small Molecule Inhibitors

Publications

 The specifities of protein kinase inhibitors: an update
— Jenny Bain, Hilary Mclauchlan, Matthew Elliott, Philip Cohen

 Specificity and mechanism of action of some commonly used protein kinase inhibitors
— Stephen P. Davies, Helen Reddy, Matilde Caivano, Philip Cohen


 Mechanistic considerations in high-throughput screening
— Robert A. Copeland

Inhibition Data

Kinase Inhibition Profile — Staurosporine.
Graphic illustrates the effect of Staurosporine (1 μM) on a wide variety of protein kinases assayed at 10 μM ATP

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