Ion Channel Services

Millipore is pleased to offer a fully validated panel of functional profiling assays which employ a variety of PrecisION ion channel cell lines, the IonWorks HT/Quattro instrument platforms, the PatchXpress and conventional manual electrophysiology platforms. The cell lines were carefully selected for optimal performance on the IonWorks instrument thus ensuring a high level of accuracy and precision in the assays.

CardiacProfiler Service

Excitation and relaxation of cardiac muscle is regulated by a complex and dynamic interplay of ionic currents passing through a variety of different ion channels. A number of these channels are genetically linked with long QT syndrome (LQT), suggesting that alteration of function (e.g., modulation by drugs) could also produce life-threatening arrhythmias independently of hERG
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IonChannelProfiler Service

Now you can access a whole range of ion channel assays that support different types of screening cascade, from HTS through lead optimization and SAR studies. Whether it’s a 50,000 compound screen against an individual target, profiling compound sets against a selectivity panel or a detailed biophysical study of a single compound, Millipore has the expertise and technology to rapidly deliver the high quality data you need.
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FlexLab Service

Our FlexLab provides you with experience, expertise and the flexibility you require to drive your discovery program. We can also develop custom ion channel cell lines and assays, or work with your own validated cell lines.
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