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Millipore Technical Library - Frequently Asked Questions

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What is the compatibility of Durapore with high pH solutions?

The upper recommended pH limit for Durapore membranes is 10. At pH > 10, the hydrophilization layer of the membrane may become subject to hydrolysis. The extent of hydrolysis is a function of time, temperature , concentration and time of exposure. Upon exposure to high pH, the hydrophylization layer can swell which could result in a loss of permeability or flux. The hydrolysis of the hydrophilic layer will also lead to increased extractables from the membrane.