Purification & Concentration
To accelerate your research, spend your time thinking about biology, not worrying about the quality of your reagents. At Millipore, we are committed to giving you peace of mind. For decades, we have perfected our membrane filtration technologies for consistent quality, low extractables, and low nonspecific binding.
Each time you use Millipore’s purification and concentration tools for your proteins, nucleic acids, or viruses, you’ll be saving time while maximizing purity and yield. But you won’t be thinking about it, you’ll be coming up with the next great idea to move your discoveries forward.
Protein purification and concentration
For reproducible protein assay results, you need to purify your protein of interest without denaturing it, losing its enzymatic activity or binding functions. Concentrate it without compromising yield, even if it’s labile or low in abundance. Luckily, Millipore offers several fast, gentle, membrane-based options for concentrating and fractionating your protein, and our PureProteome magnetic beads are perfect for His-tag or antibody-mediated purifications.- PureProteome magnetic beads
- Easy, fast centrifugal sample concentration, desalting, and buffer exchange
- Starting volume <1 mL
- Starting volume <4 mL
- Starting volume <15 mL
- Starting volume <70 mL - High-throughput protein concentration and desalting
- Diafiltration with stirred cells
- Clarification with Pellicon tangential flow microfiltration
- Pellicon tangential flow ultrafiltration
Nucleic acid purification and concentration
Given the ever-increasing complexity of your genetic manipulations, purification and concentration of nucleic acids shouldn’t be a rate-limiting step. With our membrane-based technologies, you can eliminate time-consuming precipitation steps for clean, high yields of DNA or RNA. For higher throughput molecular biology, use our Multiscreen plate-based tools that allow you to process up to 384 samples at once, either manually or using automation.- Easy, fast centrifugal sample concentration, desalting and buffer exchange
- Starting volume <1 mL
- Starting volume <4 mL
- Starting volume <15 mL
- Starting volume <70 mL - High-throughput PCR purification
- Plasmid and BAC preparation
- DNA extraction from agarose gels
- Purification with Multiscreen plates
Virus purification and concentration
You’ve spent weeks optimizing the growth of your delicate target cells for viral infection. Now you need reliable, concentrated virus for efficient transduction and minimal toxicity. Millipore’s Fast-Trap Virus Purification and Concentration kits let you purify and concentrate your virus in as little as two hours with excellent yield and purity. Achieve reproducibility at last by using Fast-Trap kits for lentivirus, adenovirus or adeno-associated virus.
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