IonChannelProfiler Service
Now you can access a whole range of ion channel assays—based on automated and manual patch clamp electrophysiology—that support different types of screening cascade, from HTS through lead optimization and SAR studies. Whether it’s a ion channel screening of 50,000 compounds, profiling compound sets against a selectivity panel or a detailed biophysical study of a single compound, we have the expertise and technology to rapidly deliver the high quality data you need.
Ion Channel Genes Associated with Inherited Long QT Syndrome
|
LQT1 |
KCNQ1 |
30-35% |
LQT2 |
hERG |
25-30% |
LQT3 |
NaV1.5 |
5-10% |
LQT5 |
minK |
1% |
LQT6 |
MIRP1 |
Rare |
LQT7 |
Kir2.1 |
Rare |
LQT8 |
CaV1.2 |
Rare |
LQT10 |
NaV1.5 |
Rare |
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