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GPCRProfiler Service
Safety & Disease Panels

Millipore is the premier provider of functional cell-based assays for GPCR screening and profiling. Whether you need to profile your lead compounds to evaluate potential side-effects or identify the therapeutic target for a biologically active molecule, GPCRProfiler Service Safety and Disease Panels can help you choose which GPCR targets will best address your research needs.

With GPCRProfiler Service, you receive:
  • The flexibility to choose from 1 to 140 different receptors to screen against
  • Your choice of 15 different service panels, including more than 57 distinct ligand families, 2 safety panels and 11 disease-focused panels
  • A functional readout that includes both agonist and antagonist data
  • The experience and knowledge of the Millipore scientists—the assay experts

PanelsSubcategories, target tissues and/or description
FULLComplete listing of receptors available on the GPCRProfiler service panel.
DIVERSITYDiverse collection of receptors, including one representative member of each ligand family.
SAFETY PANELSBroad Safety - A comprehensive panel of receptors with known or anticipated side-effects or liabilities.
Focused Safety - A focused panel of receptors known to be linked to common side-effects or liabilities.
DISEASE PANELSCancer
Cardiovascular - Heart, Thrombosis, Angiogenesis, Atherosclerosis, Hypertension, Flushing
Digestive & Renal - GI, Renal, Liver, Urinary, Prostate
Inflammation - Inflammation / Arthritis, Allergy, Itching, Dermatitis, Sepsis, Fever, Immunosuppression, Viral infection, HIV, MS, WHIM
Metabolic - Appetite, Diabetes, Metabolic, Obesity, Dry mouth, Growth, Hyperthyroidism, Body Temperature Regulation, Osteoporosis, Calcium Homeostasis
Neurological Disorders - Parkinson’s, Epilepsy, Cognition, Neuroprotection, Alzheimer’s, Nausea, MS
Psychiatric Disorders - Psychosis, Depression, Mood / Anxiety, Addiction, Tourette’s, ADHD
Reproduction - Reproduction, Fetal Development, Pre-term Labor, Newborn Health
Respiratory - Respiratory, Asthma
Sensory - Pain, Migraine, Vision, Macular Degeneration, Pupil Size, Glaucoma, Auditory, Smell
Sleep - Sedation, Narcolepsy


   Download the datasheet to view the full list of GPCRProfiler Service Safety & Disease Panels

To Place an Order for GPCRProfiler Service Safety & Disease Panels:

Cross-Target Safety & Liability Screening
Millipore offers a unique cross-target service panel for early drug discovery screening against a liability-focused functional assay panel of GPCRs, ion channels, kinases and phosphatases.
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