Billerica, MA – May 12, 2010 – Millipore Corporation (NYSE: MIL), a leading provider of technologies, tools and services for the global life science industry, today announced the launch of FlowCellect™ kits for the analysis of cell health using flow cytometry. The kits permit researchers to quickly and easily evaluate mitochondrial health in drug compound screening, apoptosis-related research, and understanding the mechanism of diseases.

“Mitochondrial health and cell health are intimately related, and flow cytometry is an ideal methodology to study this inter-relationship,” said Kamala Tyagarajan, Ph.D. Senior R&D Manager at Millipore. Mitochondria are important cellular organelles that maintain cellular energy balance and control cell survival as a part of apoptosis regulation. Mitochondrial dysfunction is often an early indicator of cellular stress and very often triggers apoptosis or other cell death pathways.

The six newly introduced FlowCellect kits from Millipore include the MitoDamage Kit, which provides simultaneous information on mitochondrial perturbations, apoptosis and cell death, and the MitoStress kit, which allows study of the inter-relationship between mitochondrial oxidative stress and apoptosis. For researchers who want to further understand mechanistic pathways, Cytochrome C kits allow for evaluation of mitochondrial Cytochrome C levels in apoptotic cells and commitment to the intrinsic pathway of death, thereby simplifying an assay that has traditionally been done with western blots.

The kits may be utilized on any flow cytometer equipped with blue and red lasers. However, given the multiplicity of samples that need to be screened and the variety of treatment conditions that need to be evaluated in screening or apoptosis studies, guava® benchtop flow cytometers are a more effective solution for researchers working in this space.

“By combining FlowCellect Mitochondrial/Cell Health kits with the power of the easyCyte™ 8HT Flow Cytometry System and the heat-map and dose response features of Incyte™ software, researchers can obtain multiplexed answers on a large number of samples simultaneously,” said Tyagarajan. “The simplicity of the assays will help migrate such studies out of the core lab to the lab bench and enable researchers from multiple disciplines to mine mitochondrial and cell health information with ease.”

Additional Resources
www.millipore.com/mitohealth

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About Millipore

Millipore (NYSE: MIL) is a life science leader providing cutting-edge technologies, tools, and services for bioscience research and biopharmaceutical manufacturing. As a strategic partner, we collaborate with customers to confront the world’s challenging human health issues. From research to development to production, our scientific expertise and innovative solutions help customers tackle their most complex problems and achieve their goals. Millipore Corporation is an S&P 500 company with more than 6,000 employees worldwide. For more information, visit www.millipore.com.

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Millipore Media Contact

Greg Hoff
Media Relations
Bioscience Division
978-762-5170
greg_hoff@millipore.com

Millipore, Advancing Life Science Together, and guava are registered trademarks and the “M” logo, easyCyte, and FlowCellect are trademarks of Millipore Corporation.