Millipore Announces Protocol for the Concentration of Genomic DNA for Forensic Analysis

Billerica, Massachusetts --- November 30, 2006 --- Millipore Corporation today announced the availability of a faster protocol using Amicon® Ultra-4 100K NMWL centrifugal filter devices to concentrate human genomic DNA to be used in forensic analysis. Amicon Ultra-4 devices can quickly ultrafilter dilute nucleic acid samples for fast separation of genomic DNA from low molecular weight compounds and analysis inhibitors.

The source material for forensic analysis is typically blood or blood stains, bodily fluids and/or tissue samples obtained either from crime scenes, directly from individuals, or from human remains. The isolated genomic DNA is used to identify individuals based on their Short Tandem Repeat (STR) profile. The resulting STR genetic fingerprints are unique to each person and can provide unequivocal identification of an individual.

The Amicon Ultra device design is compatible with the multiple spin recovery assays used for STR analysis. The concentrated DNA is collected from the filter unit sample reservoir, while the ultrafiltrate can be collected in the provided centrifuge tube if desired. The Amicon Ultra centrifugal devices incorporate the Ultracel® low-binding ultrafiltration membrane in a vertical housing design to deliver high sample recoveries with 10-minute spin times. In addition, Amicon Ultra devices allow for direct pipette sample access and are compatible with most rotor types. Amicon Ultra-4 devices are available in packs of 8, 24, and 96 filter units, which come assembled with centrifuge tubes and caps.

Millipore’s Bioscience Division provides innovative tools, services and biological reagents that drive advancements in biomedical and academic research as well as support the discovery and development of new pharmaceuticals. Our customers work in leading research laboratories across a variety of industries throughout the world. Millipore improves their laboratory productivity and efficiency through optimized workflows. For more information, please contact Millipore Tech Service at 1-800-MILLIPORE, 781-533-6000 or visit www.millipore.com.

About Millipore

Millipore is a leading provider of products and services that improve productivity in laboratory research and bioprocessing manufacturing sites. Through its broad product portfolio, the Company drives growth through innovation and delivers higher value-added applications to the marketplace. Millipore experts have a comprehensive understanding of customers’ research, which results in superior tools, technologies and services. The Company is part of the S&P 500 index and employs approximately 5,800 employees in more than 47 offices worldwide. For additional information on Millipore Corporation, please visit www.millipore.com.

Millipore, Amicon and Ultracel are registered trademarks of Millipore Corporation.

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Millipore Corporation
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karen_gobler@millipore.com

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