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Millipore and CXR Biosciences Announce New Drug Screening Platform Products


Billerica, Massachusetts and Dundee, Scotland --- March 6, 2007 --- Millipore Corporation in collaboration with CXR Biosciences Ltd. today announced their first jointly developed products for the pre-clinical drug development marketplace. Announced as a joint co-development agreement in 2005 (with Upstate), this partnership strengthens Millipore’s increasing presence in the preclinical drug testing market and launches CXR’s entry into the reagent industry.

These products, several of which address unmet market needs, are antibodies that identify key enzymes and transcription factors important in drug metabolism and its regulation. The product portfolio includes:

Human Cytochrome P450 CYP2D6
Human Cytochrome P450 CYP2A6
Human Cytochrome P450 Reductase (POR)
Human Pregnane X Receptor (PXR)
Human Constitutive Androstane receptor (CAR)
Human Farnesoid X Receptor (FXR) (27 to 143)
Human Farnesoid X Receptor (FXR) (322 to 472)

This product platform enables safe drug compounds to be identified sooner and allows only the molecules most likely to succeed in the clinic to advance. Early compound identification makes it possible to reduce the development time for new therapies. Future co-development efforts will be focused on building predictive toxicity and drug metabolism screens to profile compounds in various cell based and in vitro assays.

Millipore’s Bioscience Division provides innovative tools, services and biological reagents that drive advancements in biomedical and academic research as well as support the discovery and development of new pharmaceuticals. The product portfolio has been further enhanced with the 2006 addition of Chemicon®, Upstate® and Linco® product lines, allowing Millipore to provide the most complete offering of life science tools on the market. Our customers work in leading research laboratories across a variety of industries throughout the world. Millipore improves their laboratory productivity and efficiency through optimized workflows. For more information, please contact Millipore Tech Service at 1-800-548-7853 or 951-676-8080 or visit


About Millipore

Millipore is a leading provider of products and services that improve productivity in biopharmaceutical manufacturing and in clinical, analytical and research laboratories. The Company is organized in two operating divisions. Its Bioprocess Division helps enables pharmaceutical and biotechnology companies to optimize their manufacturing productivity, ensure the quality of drugs, and scale up the production of difficult-to-manufacture biologics. Its Bioscience division helps to optimize laboratory productivity and workflows. Its products and enabling technologies that are used in the laboratory are essential for the research and development of biologically based life science therapeutics. Millipore has a deep understanding of its customers’ research and manufacturing process needs, and offers reliable and innovative tools, technologies and services. The Company is part of the S&P 500 index and employs approximately 5,800 employees in more than 47 offices worldwide. For additional information on Millipore Corporation, please visit its website at: www.millipore.com.



About CXR Biosciences

CXR Biosciences is a solutions provider applying new models and approaches for drug discovery and development, and the assessment of risks to humans of chemicals. CXR applies a combination of extensive experience in pre-clinical development and risk assessment, together with the application of proprietary post-genomic models for the evaluation of drug metabolism and toxicity. CXR works with over 50 customers and collaborators, including major pharmaceutical companies, industrial chemical companies and small drug discovery companies. CXR Biosciences Ltd. is located in Dundee, Scotland. For more information, please visit our website: www.cxrbiosciences.com


Chemicon, Linco, and Upstate are registered trademarks of Millipore Corporation.



MILLIPORE NEWS
For immediate release
Media Contact:

Karen Gobler
Communications Manager
Millipore Corporation
978-762-5294
karen_gobler@millipore.com

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