Millipore Optimizes Protein Fractionation Using Ultrafiltration

Billerica, Massachusetts --- October 20, 2006 --- Millipore Corporation today announced the development of a protocol for efficiently compartmentalizing protein solutions using ultrafiltration in a centrifugal mode. Traditional fractionation techniques utilize size-exclusion chromatography, which is both laborious and time intensive. Comparatively, the new method confirms the advantage of speed and efficiency through a combination of Millipore’s Amicon® Ultra centrifugal devices and expertise.

Amicon Ultra centrifugal devices enable researchers to fractionate protein mixtures quickly and easily due to the product design. The bi-vertical housing limits membrane polarization, while the hydrophilic microstructure of low-binding Ultracel® ultrafiltration membrane enables efficient protein separation. This method expedites the fractionation process by minimizing process steps such as setting up columns, optimizing column flow rates, and collecting and concentrating various fractions.

Fractionation is a process for separating a mixture into its component parts to eliminate the complexity of the proteome. Common applications for this technique include biomarker analysis from serum, protein purification, 2D-PAGE and sample preparation for mass spectrometry analysis for those scientists in university, pharmaceutical and biomedical laboratories performing protein research.

Millipore’s Bioscience division delivers complete solutions and services for pharmaceutical, academic, life science, clinical and government research laboratories. With more than 50 years of experience, Millipore manufactures and markets several thousands of products that accelerate drug screening and improve sample preparation. For more information, please contact Millipore Tech Service at 1-800-MILLIPORE, 781-533-6000 or visit www.millipore.com.

About Millipore

Millipore is a leading provider of products and services that improve productivity in biopharmaceutical manufacturing and in clinical, analytical and research laboratories. The Company is organized in two operating divisions. Its Bioprocess Division helps enables pharmaceutical and biotechnology companies to optimize their manufacturing productivity, ensure the quality of drugs, and scale up the production of difficult-to-manufacture biologics. Its Bioscience division helps to optimize laboratory productivity and workflows. Its products and enabling technologies that are used in the laboratory are essential for the research and development of biologically based life science therapeutics. Millipore has a deep understanding of its customers’ research and manufacturing process needs, and offers reliable and innovative tools, technologies and services. The Company is part of the S&P 500 index and employs approximately 5,800 employees in more than 47 offices worldwide. For additional information on Millipore Corporation, please visit its website at: www.millipore.com.

Amicon, Ultracel and Millipore are registered trademarks of Millipore Corporation.

MILLIPORE NEWS
For immediate release
Media Contact:
Karen Gobler
Communications Manager
Millipore Corporation
978-762-5294
karen_gobler@millipore.com

Media Contact

For media inquiries, company news and community outreach:

Karen Marinella Hall
Director, Corporate Communications
Tel: 978-715-1567
Karen_Hall@millipore.com

Sustainability

Our commitment to environmental stewardship.

» More

Find A Location

Find the Millipore office or expert closest to you.

Contact Us

We want to hear from you. Contact a specific department below or click "Suggestions and Feedback" to send your comments.