Microbiology: Air Monitoring - Overview

Maintain Compliance with Regulatory Requirements


	Microbial contamination can exist in the valves or lines that feed compressed gas and air into critical, aseptic manufacturing environments. Millipore’s M Air T Tester for Compressed Gas yields fast and reliable results, permitting accurate microbial monitoring of the gasses and air that pass through these lines.

Environmental monitoring is required for aseptic manufacturing processes and controlled areas such as isolators and barrier environments. Microbiological monitoring of air is a Good Manufacturing Practice (GMP) requirement. Air monitoring helps you assess the effectiveness of cleaning and sanitizing practices, identify potential routes of contamination, and take corrective actions before contamination occurs.

Millipore’s M Air T system features a unique cassette design for determining the presence of viable, airborne microorganisms in critical areas. The system impacts microorganisms onto an agar surface, which is an allowed method for analyzing microbial air contamination (USP and EU-GMP guidelines).

Find Your Complete Solution for Air Monitoring

Millipore offers both products and services to provide you with a complete solution for your air monitoring test requirements. Products include the M Air T Portable Air Tester, the M Air T Air Tester for Isolator, the M Air T Tester for Compressed Gas, M Air T agar cassettes, and single and dual chamber incubators. Air monitoring systems must be calibrated to conform to GMP requirements. Millipore’s service specialists can calibrate your M Air T system, or you can calibrate the system yourself using the M Air T calibration kit. The kit contains everything you need: flow meter, flow rate correction table, instruction manual, calibration sieve, and calibration certificate. Millipore’s validation and maintenance services provide you with the support you need to obtain consistent test results and ensure the longevity of your equipment.

Achieve Optimal Air Monitoring

The M Air T system makes following the regulatory requirements that lead to optimal air monitoring easy. The programmable memory retains your air velocity settings allowing you to sample the air at an adequate impaction speed. The convenient pre-filled agar cassettes, containing 20g agar with a minimal depth of 6mm, limit media dehydration during the sampling cycle. The agar cassettes are simple to load without any risk of contamination. The consistent fill level and flat surface of the agar cassettes ensure that you sample the same volume of air during every test. The M Air T sieve has 967 holes to optimize colony distribution and reduce colony overlapping. An integrated grid makes enumerating colonies straightforward.

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