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Final Aseptic Filling

Millipore recommends running small-scale trials for capacity and throughput screening for the best candidates. If capacity data illustrates that fluid is a non-plugging stream (³1,000 L/m2) then sizing is based on flow rate and pressure drop requirements.

Millipore recommends normalizing for pressure and area of the OptiScale small-scale screening capsules. This table provides details on process development devices for recommended filters and alternatives since the ideal solution will vary based on each fluid stream. The following order table is for recommended devices only.

Filter FormatArea/FilterCatalogue No.
OptiScale Devices
    Milligard SC 1.2 µm + 0.5 µm membrane
13.8 cm2SWSCA47FF
    Milligard SS 0.5 µm + 0.2 µm membrane
13.8 cm2SWSSA47FF3
    Milligard 1.2 µm membrane
13.8 cm2SW19A47FF3
    Milligard 0.5 µm membrane
13.8 cm2SW06A47FF3
    Milligard 0.2 µm membrane
13.8 cm2SW03A47FF3
OptiScale Devices
    Durapore 0.22 µm membrane
13.8 cm2SVGLA47FF3
    Millipore Express SHF 0.2 µm membrane
13.8 cm2SGEPA47FF3
    Double-layer Millipore Express SHC 0.5 µm + 0.2 µm membrane
13.8 cm2SHGEA47FF3