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Plasma Fractionation

Millipore recommends running small-scale trials for capacity and throughput screening. This table provides details on process development devices for recommended filters and alternatives since the ideal solution will vary based on each fluid stream. The following order table is for recommended devices only.

Albumin
Filter FormatArea/FilterCatalogue No.
Pellicon XL50 Cassettes
    Biomax 10 kD membrane
50 cm2 PXB010A50

OptiScale Capsules
    Double-layer Milligard SS 0.5 μm + 0.2 μm membrane
13.8 cm2SWSSA47FF3
    Double-layer Polysep II W3 1.0 μm + 0.2 μm membrane
13.8 cm2 SGW3A47FF3
    Durapore 0.22 μm membrane
13.8 cm2SVGLA47FF3
    Millipore Express SHF 0.2 μm membrane
13.8 cm2SGEPA47FF3

OptiScale Capsules
    Single-layer Grade 55DE
23 cm2 M55DE23HH3
    Double-layer Grade C0HC
23 cm2MC0HC23HH3
IgG Hyper Immune
Filter FormatArea/FilterCatalogue No.
Pellicon XL50 Cassettes
    Biomax 10 kD membrane
50 cm2PXB010A50
    Biomax 30 kD membrane
50 cm2 PXB030A50
    Biomax 50 kD membrane
50 cm2PXB050A50
    Ultracel PLC 30 kD membrane
50 cm2 PXC030C50

Pellicon 3 Cassettes
    Ultracel PLC 10 kD membrane
88 cm2P3C010C00
    Ultracel PLC 30 kD membrane
88 cm2P3C010C00

OptiScale Capsules
    Double-layer Milligard SS 0.5 μm + 0.2 μm membrane
13.8 cm2SWSSA47FF3
    Durapore 0.45 μm membrane
13.8 cm2SVHLA47FF3
    Durapore 0.22 μm membrane
13.8 cm2 SVGLA47FF3
    Millipore Express SHF 0.2 μm membrane
13.8 cm2SGEPA47FF3
    Double-layer Millipore Express SHC membrane
13.8 cm2SHGEA47FF3

Millistak+ Mini Capsules
    Single-layer Grade 75DE
23 cm2 M75DE23HH3
    Double-layer Grade C0HC
23 cm2MC0HC23HH3

Evaluation Kit with OptiScale-25 Capsules*
    Viresolve NFP membrane
3.5 cm2 SVPVA25NB9
    Viresolve NFR membrane
3.5 cm2SZRVA25NB9

OptiScale-40 Devices/strong>
    Viresolve Prefilter
5 cm2 SSPVA40NB9
Clotting Factors
Filter FormatArea/FilterCatalogue No.
Pellicon XL50 Cassettes
Biomax membrane is available in 5, 8,10,30,50,100,300,500 or 1,000 kD
    Biomax 10 kD membrane
50 cm2PXB010A50
    Biomax 30 kD membrane
50 cm2 PXB030A50
    Biomax 50 kD membrane
50 cm2PXB050A50

Pellicon XL50 Cassettes
Ultracel membrane is available in 5, 10, 30, 100, 300 or 1,000 kD
    Ultracel PLC10 kD membrane
50 cm2 PXC010C50
    Ultracel PLC 30 kD membrane
50 cm2 PXC030C50

OptiScale Capsules
    Double-layer Milligard SC 1.2 μm + 0.5 μm membrane
13.8 cm2SWSCA47FF3
    Durapore 0.45 μm membrane
13.8 cm2 SVHLA47FF3
    OptiScale Durapore 0.22 µm membrane
13.8 cm2SVGLA47FF3
    Millipore Express SHF 0.2 μm membrane
13.8 cm2SGEPA47FF3

Millistak+ Mini Capsules
    Single-layer Grade 65DE
23 cm2 M65DE23HH3

Evaluation Kit with OptiScale-25 Capsules
Viresolve membranes are available in an Evaluation Kit containing 9 OptiScale-25 Capsules, 3 each of 3 membrane lots, and are ideal for scale-up and scale down studies.
    Viresolve NFP membrane
3.5 cm2 SVPVA25NB9
    Viresolve NFR membrane
3.5 cm2SZRVA25NB9

OptiScale-40 Devices
    Viresolve Prefilter
5 cm2 SSPVA40NB9