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Vaccines

Millipore recommends running small-scale trials for capacity and throughput screening. This table provides details on process development devices for recommended filters and alternatives since the ideal solution will vary based on each fluid stream. The following order table is for recommended devices only.

Mammalian Cell
Filter FormatArea/FilterCatalogue No.
Prostak MF Open-Channel 2-stack Modules
    Durapore 0.22 ìm membrane ccfgggf
0.17 m2 PSGVAG021

Millistak+ Mini Capsules
    Grade B1HC
13.8 cm2MB1HC23HH3
    Grade C0HC
13.8 cm2MC0HC23HH3
    Grade D0HC
13.8 cm2MD0HC23HH3

Opticap XL1 Capsules
    Clarigard 0.3 ìm media
1-inch*K003A51TT1

OptiScale Capsules
    Double-layer Milligard SS 0.5 ìm + 0.2 ìm membrane
13.8 cm2SVSSA47FF3
    Durapore 0.22 ìm membrane
13.8 cm2 SVGLA47FF3
    Double-layer Millipore Express SHC 0.5 ìm + 0.2 ìm membrane
13.8 cm2 SHGEA47FF3

Pellicon 2 C Screen Mini-Cassettes
    Ultracel PLC C Screen 100 kD membrane
0.1 m2 P2C100C01
    Ultracel PLC C Screen 300 kD membrane
0.1 m2 P2C300C01
    Ultracel PLC C Screen 1,000 kD membrane
0.1 m2P2C01MC01
Viral Vectors
Filter FormatArea/FilterCatalogue No.
Millistak+ Mini Devices
    Grade CE40
23 cm2M40CE23HH3
    Grade CE45
23 cm2 M45CE23HH3
    Grade CE50
23 cm2 M50CE23HH3

Evaluation Kit with OptiScale-25 Capsules**
    Viresolve NFP membrane
3.5 cm2 SVPVA25NB9

OptiScale-40 Devices
    Viresolve Prefilter
5 cm2 SSPVA40NB9

OptiScale Capsules
    Durapore 0.22 ìm membrane
13.8 cm2 SVGLA47FF3
    Durapore 0.45 ìm membrane (order with 0.5 ìm prefilter SW06A47FF3)
13.8 cm2 SVHLA47FF3

Pellicon 2 V Screen Mini-Cassettes
    Ultracel PLC 300 kD membrane
0.1 m2 SVPVA25NB9
Plasmid DNA
Filter FormatArea/FilterCatalogue No.
Opticap XL1 Capsules
    Polygard CR 10 ìm media
1-inch*KR10A51TT1
    Clarigard 0.5 ìm media
1-inch* K005A51TT1

OptiScale Capsules
    Double-layer Millipore Express SHC membrane
13.8 cm2 SHGEA47FF3

Pellicon 2 V Screen Mini-Cassettes
    Ultracel PLC 30 kD membrane
0.1 m2 P2C030V01
    Ultracel PLC 100 kD membrane
0.1 m2P2C100V01

Pellicon 2 C Screen Mini-Cassettes
    Ultracel PLC 30 kD membrane
0.1 m2 P2C030V01
    Ultracel PLC 100 kD membrane
0.1 m2P2C100V01
Conjugates
Filter FormatArea/FilterCatalogue No.
Pellicon V Screen Mini-Cassettess
    Ultracel PLC 30 kD membrane
0.1 m2P2C030V01
    Ultracel PLC 100 kD membrane
0.1 m2 P2C100V01
    Ultracel PLC 300 kD membrane
0.1 m2P2C300V01
    Ultracel PLC 1,000 kD membrane
0.1 m2 P2C01MV01

Pellicon 2 C Screen Mini-Cassettes
    Ultracel PLC 30 kD membrane
0.1 m2 P2C030C01
    Ultracel PLC 100 kD membrane
0.1 m2 P2C100C01
    Ultracel PLC 300 kD membrane
0.1 m2 P2C300C01
    Ultracel PLC 1,000 kD membrane
0.1 m2 P2C01MC01

Prostak UF 4-stack Modules
    Ultracel PL 5 kD membrane
0.39 m2 PSLCSP041
    Ultracel PL 10 kD membrane
0.39 m2 PSLGSP041
    Ultracel PL 30 kD membrane
0.39 m2 PSLTSP041

OptiScale Devices
    Durapore 0.22 ìm membrane
13.8 cm2 SVGLA47FF3
    Multilayer Durapore 0.45 ìm + 0.22 ìm membrane
13.8 cm2 SHGLA47FF3
Polysaccharides
Filter FormatArea/FilterCatalogue No.
Prostak MF Open-Channel 2-stack Modules
    Durapore 0.22 ìm membrane
0.17 m2 PSGVAG021
    Durapore 0.45 ìm membrane
0.17 m2 PSHVAG021
    Durapore 0.65 ìm membrane
0.17 m2PSDVAG021

OptiScale Devices
    Double-layer Milligard LS 0.5 ìm + 0.2 ìm media
13.8 cm2 SWLSA47FF3
    Double-layer Millipore Express SHC membrane
13.8 cm2 SHGEA47FF3
    Durapore 0.22 ìm membrane
13.8 cm2 SVGLA47FF3
    Multilayer Durapore 0.45 ìm + 0.22 ìm membrane
13.8 cm2 SHGLA47FF3

Pellicon 2 C Screen Mini-Cassettes
    Ultracel PLC 30 kD membrane
0.1 m2 P2C030C01
    Ultracel PLC 100 kD membrane
0.1 m2P2C100C01

Millistak+ Mini-Capsules
    Grade B1HC
23 cm2 MB1HC23HH3

*Filter element size
**Viresolve membranes are available in an Evaluation Kit containing 9 OptiScale-25 Capsules, 3 each of 3 membrane lots, and are ideal for scale-up and scale down studies