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FAK and paxillin: regulators of N-cadherin adhesion and inhibitors of cell migration?

   
Author Schaller, Michael D
Citation Information J. Cell Biol., 166: 157-9 (2004), : (2004)
Related Products 16-233, 07-733
Pub Med ID 15263014
   

Abstract

FAK and paxillin are important components in integrin-regulated signaling. New evidence suggests that these two proteins function in crosstalk between cell-matrix and cell-cell adhesions. Further, new insight suggests that under some conditions these proteins inhibit cell migration, in contrast to their established roles in several cell systems as positive regulators of cell adhesion and migration.