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Product Reference
Dealing with energy demand: the AMP-activated protein kinase.
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| Author |
Kemp, B E, et al. |
| Citation Information |
Trends Biochem. Sci., 24: 22-5 (1999), : (1999) |
| Related Products |
07-626, 07-363, 05-673, 07-303 |
| Pub Med ID |
10087918 |
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Abstract
The AMP-activated protein kinase (AMPK) is a member of a metabolite-sensing protein kinase family that is found in all eukaryotes. AMPK activity is regulated by vigorous exercise, nutrient starvation and ischemia/hypoxia, and modulates many aspects of mammalian cell metabolism. The AMPK yeast homolog, Snf1p, plays a major role in adaption to glucose deprivation. In mammals, AMPK also has diverse roles that extend from energy metabolism through to transcriptional control.
