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Glutamate receptor subtypes localize to patches in the developing striatum.

   
Author Snyder-Keller, A and Costantini, L C
Citation Information Brain Res. Dev. Brain Res., 94: 246-50 (1996), : (1996)
Related Products AB1504, AB152, AB1506
Pub Med ID 8836585
   

Abstract

The distribution of glutamate receptors in the developing striatum of the rat was studied using antibodies specific to AMPA and NMDA subtypes. Immunocytochemistry revealed a greater density of GluR1, GluR2/3, NMDAR1, and NMDAR2A/2B receptors in patches that matched the patches of substance P-immunoreactive neurons and dopaminergic terminals. GluR1-immunoreactive patches were the most distinctive and were present already at embryonic day 19.