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Product Reference
Schwann cells influence the expression of ganglioside GD3 by rat dorsal root ganglion neurons.
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| Author |
Levison, S W and McCarthy, K D |
| Citation Information |
J. Neuroimmunol., 24: 223-32 (1989), : (1989) |
| Related Products |
MAB312R, MAB312RX, MAB312 |
| Pub Med ID |
2681262 |
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Abstract
Cultured rat dorsal root ganglion neurons expressed ganglioside GD3 when grown in the absence of non-neuronal cells. Among the non-neuronal cells, fibroblasts, but not Schwann cells, also stained for ganglioside GD3 during the first few days in culture. When neurons were combined with non-neuronal cells the intensity of the GD3 immunoreactive neuronal processes was diminished at sites contacted by Schwann cells. This contact-mediated effect was specific for ganglioside GD3 since no difference was seen with A2B5 or JONES antibodies, which recognize different gangliosides.
