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Comparison of retinal degeneration in the normal goldfish and the megalophthalmic black moor goldfish after optic nerve transection and lens extraction.

Author	Xi Ying, Maria S M Wai, Yi Wang, Jeanie P C Lau, Elizabeth Lucy Forster, David T Yew
Citation Information	The International journal of neuroscience, 119:743-52 (2009)
Keywords	Animals, Apoptosis, Goldfish, In Situ Nick-End Labeling, Lens, Crystalline, Optic Nerve Injuries, Retina, Retinal Degeneration
Related Products	S7100
Pub Med ID	19283596

A comparison in retinal degeneration was studied in the normal goldfish and the megalophthalmic goldfish after optic nerve transection or lens extraction by the TUNEL (Terminal transferase-mediated dUTP nick end labeling) technique. A significant number of TUNEL positive cells appeared in both cases 7 days after injury, with a more prominent result in the megalophthalmic eye. Lens extraction, had less apoptotic cell death in the experimental retinas.