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Immune changes in post-menopausal osteoporosis: the Immunos study.

   
Author V Breuil,M Ticchioni,J Testa,C H Roux,P Ferrari,J P Breittmayer,C Albert-Sabonnadière,J Durant,F De Perreti,A Bernard,L Euller-Ziegler,G F Carle
Citation Information Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 21: (2010)
Keywords Aged,Aged, 80 and over,B-Lymphocyte Subsets,Body Composition,Case-Control Studies,Dendritic Cells,Estrogens,Female,Granulocyte-Macrophage Colony-Stimulating Factor,Humans,Immunity, Cellular,Immunophenotyping,Interferon-gamma,Middle Aged,Osteoporosis, Postmenopausal,Osteoporotic Fractures,Pilot Projects,T-Lymphocyte Subsets
Related Products HBN51K1RANKL
Pub Med ID 19876583
   

Abstract

The phenotypic and functional characteristics of immune cells of osteoporotic women compared to healthy controls similar for age and estrogen level showed for the first time significant changes in several B lymphocytes populations in postmenopausal osteoporosis, related to bone mineral density (BMD) and fractures, and a significant lower basal secretion of interferon-gamma (IFN-gamma) by CD4(+).