Product Reference
A continuum of cell states spans pluripotency and lineage commitment in human embryonic stem cells.
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| Author |
Shelley R Hough,Andrew L Laslett,Sean B Grimmond,Gabriel Kolle,Martin F Pera |
| Citation Information |
PloS one, 4: (2009) |
| Keywords |
Blastomeres,Cell Differentiation,Cell Lineage,Drosophila Proteins,Embryonic Stem Cells,Epidermal Growth Factor,Flow Cytometry,Gene Expression Regulation,GPI-Linked Proteins,Humans,Intercellular Signaling Peptides and Proteins,Membrane Glycoproteins,Models, Biological,Neoplasm Proteins,Octamer Transcription Factor-3,Pluripotent Stem Cells,Stem Cells,Transcription, Genetic |
| Related Products |
SCR055 |
| Pub Med ID |
19890402 |
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Commitment in embryonic stem cells is often depicted as a binary choice between alternate cell states, pluripotency and specification to a particular germ layer or extraembryonic lineage. However, close examination of human ES cell cultures has revealed significant heterogeneity in the stem cell compartment.
